Feline upper respiratory tract infection due to Aspergillus spp. is considered an emerging disease, with the number of reported cases continuing to rise. In this study, we report the first case of feline sinonasal aspergillosis caused by Aspergillus fischeri in Japan. The patient presented after 2 months of progressive facial deformity around the nose and nasal discharge. The isolate from this ...

BACKGROUND AND PURPOSE Candidaalbicans is the most common causative agent of candidiasis. Candidiasis management is dependent on the immune status of the host, severity of disease, and the choice of antifungal drug. Antifungals, specifically triazoles, are widely administered for the treatment of invasive fungal infections. Herein, we aimed to evaluate the invitro susceptibility of C.albicans i...

Leishmaniasis, caused by protozoan parasites of the Leishmania genus, is one of the most prevalent neglected tropical diseases. It is endemic in 98 countries, causing considerable morbidity and mortality. Pentavalent antimonials are the first line of treatment for leishmaniasis except in India. In resistant cases, miltefosine, amphotericin B and pentamidine are used. These treatments are unsati...

This study investigates the effects of nanofillers on interfacial transition zone (ITZ) between aggregate and cement paste by using nanoindentation statistical techniques. Moreover, underlying mechanisms are revealed through micromechanical modeling. The results indicate that incorporating increases degree hydration in ITZ, reduces content micropores low-density calcium silicate hydrate (LD C–S...

background and purpose: candida albicans is the most common causative agent of candidiasis. candidiasis management is dependent on the immune status of the host, severity of disease, and the choice of antifungal drug. antifungals, specifically triazoles, are widely administered for the treatment of invasive fungal infections. herein, we aimed to evaluate the in vitro susceptibility of c. albica...

Aminotetrazole compounds have become attractive ingredients in gas generating compositions, solid rocket propellants, and green pyrotechnics. Therefore, a fundamental understanding of their thermal decomposition mechanisms and thermodynamics is of great interest. In this study, the specular reflection isopotential searching method was used to investigate the unimolecular decomposition mechanism...

We tested a general method for the identification of drug resistance loci in the trypanosomatid protozoan parasite Leishmania major. Genomic libraries in a multicopy episomal cosmid vector were transfected into susceptible parasites, and drug selections of these transfectant libraries yielded parasites bearing cosmids mediating resistance. Tests with two antifolates led to the recovery of cosmi...

8 This paper presents an image analysis procedure using Euclidean Distance Mapping to compute microstructural 9 gradients at interfaces in composite materials. This method is capable of producing phase distribution plots at 10 single pixel strip width very quickly and efficiently. Compared to conventional dilation-subtraction strip 11 analysis, the new method is faster, more flexible and is not...

The use of the agar diffusion Neo-Sensitabs method to determine antifungal susceptibility of 59 isolates of dermatophytes, namely Epidermophyton floccosum, Microsporum canis, M. gypseum, Trichophyton mentagrophytes, T. rubrum and T. tonsurans to Clotrimazole (CLZ), Itraconazole (ITZ) and Terbinafine (TBF) is described. Results obtained are compared to the minimum inhibitory concentrations (MIC)...

BACKGROUND Candida glabrata is a pathogenic yeast with several unique biological features and associated with an increased incidence rate of candidiasis. It exhibits a great degree of variation in its pathogenicity and antifungal susceptibility. OBJECTIVES The aim of the present study was to evaluate the in vitro antifungal susceptibilities of the following six antifungal drugs against clinic...