The distribution of the breakpoints in the karyotypes of workers occupationally exposed to benzene was tested. Fifty-six workers exposed to benzene were investigated cytogenetically. A significant increase in chromosome aberrations was observed. The distribution of the breakpoints in the karyotypes of examined workers was significantly nonrandom (p less than or equal to 0.001). The breakpoints ...

The study by Greve and colleagues, in this issue of Cancer Research, provides new molecular insights into the intriguing clinical activity DNA hypomethylating agents (HMA) patients with acute myeloid leukemia (AML) monosomal karyotypes. Patients AML adverse karyotypes are known to benefit from HMAs, but not cytarabine, a cytidine analog without HMA activity, specific mechanisms remain poorly un...

The karyotypes of three species of Pyrgomorphidae grasshoppers were studied: Zonocerus elegans (Thunberg, 1815), Pyrgomorpha guentheri (Burr, 1899) and Atractomorpha lata (Mochulsky, 1866). Data on karyotypes of P. guentheri and Z. elegans are reported here for the first time. All species have karyotypes consisting of 19 acrocentric chromosomes in males and 20 acrocentric chromosomes in females...

Karyotypes of two species of the African annual killifish genus Nothobranchius Peters, 1868, Nothobranchius brieni Poll, 1938 and Nothobranchius sp. from Kasenga (D.R. Congo) are described. Both species displayed diploid chromosome number 2n = 49/50 for males and females respectively with multiple-sex chromosome system type X1X2Y/X1X1X2X2. The karyotypes of studied species are considerably diff...

The karyotypes of 76 males and 84 females, each assembled by the trypsin banding method, are examined in a study designed to investigate sex differences among autosomes. It is shown that female autosomes have consistently larger surface areas than the males, with respect to both the short and long arm measurements. In addition, discriminant function analysis is used to distinguish between the m...

The karyotypes of 100 males and 100 females, each assembled by the trypsin banding method, are examined in a study designed to investigate sex differences among autosomes. It is shown that female autosomes are consistently longer than those of the males, with respect to both the short and long arm measurements. In addition, discriminant analysis is used to distinguish between the male and femal...