Keratins are tough, fibrous proteins found as the major protein component in hair. Chemical hair removal is harsh and results severe toxicity pollution, hence, a need for non-chemical enzymatic process. The aim of this study to characterise keratinase from isolated keratin-degrading Bacillus licheniformis-K51, subtilis-K50 sp.-K53 investigate its potential removal. collagenolytic ability kerati...

Background: Subtilisin –like proteases are the group of proteases including keratinases found in dermatophytes which degraded keratin. Determination of the proteases activity of Trichophyton vanbreuseghemii isolates which were obtained from soil and clinical and soil isolates of Microsporum gypseum in Iran and characterization of their genome were aim of present study. Methods: Ezymatic activit...

Keratinases are enzymes of great importance involved in pathogenic processes of some fungi. They also have a widespread ecological role since they are responsible for the degradation and recycling of keratin. On the one hand, studying them furthers our knowledge of pathogenicity mechanisms, which has important implications for human health, and on the other hand, understanding their ecological ...

An increasing quantity of chickens is being utilized annually in the poultry industry, producing a huge volume of chicken feather waste which presents a high quality supply of keratin. Keratinases possessing high level of keratinolytic activity on insoluble keratin play a crucial role in hydrolyzing chicken feathers. Ever since the discovery of proteolytic ability as well as water solubility of...

Keratinases are a group of proteolytic enzymes that display the capability of degrading insoluble keratin substrates such as feather resulting as poultry waste. Entrapment of crude/purified enzyme within a matrix is a common method for immobilization. An immobilized enzyme provides increased resistance to changes in conditions such as pH or temperature. It also allows enzymes to be held in plac...

BACKGROUND This study was carried out to determine growth of dermatophytes using human stratum corneum in vitro and the degrading effect of Keratinases (Proteinases) on stratum corneum for a complete understanding of the host parasite relationship. METHOD Trichophyton rubrum isolates derived from patients with tinea cruris infections were obtained from the Department of Medical Microbiology, ...

The Actinomycetes comprise a ubiquitous order of bacteria which exhibits wide physiological and morphological diversity. These microorganisms are particularly abundant in alkaline soils rich in organic matter. Keratin is an insoluble structural protein of skin, and its derivatives (e.g. feather, hair, wool and horn) are known for their high stability. Actinomycetes producing keratinases are hav...

Extremophiles are bizarre microorganisms that can grow and thrive in extreme environments, which were formerly considered too hostile to support life. The extreme conditions may be high or low temperature, high or low pH, high salinity, high metal concentrations, very low nutrient content, very low water activity, high radiation, high pressure and low oxygen tension. Some extremophiles are subj...

Keratinases are exciting keratin-degrading enzymes; however, there have been relatively few studies on their immobilization. A keratinolytic protease from Chryseobacterium sp. kr6 was purified and its partial sequence determined using mass spectrometry. No significant homology to other microbial peptides in the NCBI database was observed. Certain parameters for immobilization of the purified ke...

Feed industries are seeking new ways to cope with increased raw material costs, and one approach is to apply enzymatic treatment in the production of feed ingredients from animal by-products. Keratinases, a group of proteases, are capable of hydrolyzing keratin-rich material and have been applied in the production of cost-effective feather by-products for use as feed and fertilizers. The curren...