conclusions diabetes may be caused by toxoplasma gondii. presence of t. gondii in the pancreas at the same time could directly undermines the pancreas cells. when β cells are destroyed, insulin secretion would then be affected. probably the destruction of t. gondii affects nervous system and damages pancreatic cells leading to increased risk of diabetes. results the prevalence of igg antibodies...

This study aimed to evaluate three sets of B1 gene DNA primer for the diagnosis Toxoplasma gondii. The gondii that stored on liquid nitrogen was isolated using DNAzol™ reagent. first step Polymerase Chain Reaction (PCRs) performed external and internal sets, respectively, then nPCR. PCR products sequencing by Apical Science. All sequences were analysed CLC Sequence Viewer Version 8.0 software c...

We report herein anti-proliferation effects of 4-arylthiosemicarbazides, with a cyclopentane substitution at N1 position, on highly virulent RH strain Toxoplasma gondii. Among them, the highest in vitro anti-Toxoplasma activity was found meta-iodo derivative. Further experiments demonstrated inhibitory thiosemicarbazides tyrosinase (Tyr) activity, and good correlation between percentage Tyr inh...

Cats are the definitive hosts of Toxoplasma gondii. Infected cats excrete oocysts in their feces, infecting humans and other animals. The objective of the present study was to determine the presence of anti-Toxoplasma antibodies in cat owners and their pets, and determine if there was a relationship between Toxoplasma infection and humans who live with infected cats. IgG anti-Toxoplasma antibod...

Variations in the prevalence of antibody to toxoplasma gondii is reported from various countries (Hong Kong 9.8%, London 22%, New York 30%, Paris 84%) and from various cities in the same country(Jeddah 32%, Abha 51%). An area densely populated with cats is believed to be heavily contaminated with toxoplasma oocysts, leading to an increasing infection. As MedinaMunawarah has a large number of ca...

Toxoplasma gondii is a unicellular parasite that causes severe brain and eye disease. Current drugs for T. gondii are limited by toxicity. Bumped kinase inhibitors (BKIs) selectively inhibit calcium-dependent protein kinases of the apicomplexan pathogens T. gondii, cryptosporidia, and plasmodia. A lead anti-Toxoplasma BKI, 1294, has been developed to be metabolically stable and orally bioavaila...

Cite this article: Claudia F. Dick.” Toxoplasma gondii: The Mind-Control Parasite”. J J Srgy Volume 1, Issue 1: 006 Toxoplasma gondii is an extremely widespread protozoan parasite, with a prevalence of 20-70% in USA. This high prevalence is attributable in part to the HIV pandemic: neurotoxoplasmosis is the most frequent oportunistic infection and the most common cause of brain focal injuries i...

Toxoplasma gondii (T. gondii) microneme protein 8 (MIC8) represents a novel, functional distinct invasion factor. In this study, we generated virus-like particles (VLPs) targeting Toxoplasma gondii MIC8 for the first time, and investigated the protection against highly virulent RH strain of T. gondii in a mouse model. We found that VLP vaccination induced Toxoplasma gondii-specific IgG and IgG1...

Anti-Neospora caninum antibody was detected in anti-Toxoplasma gondii positive and negative human sera by ELISA, western blot and immunofluorescence assay (IFA). Twelve cases out of 172 (6.7%) Toxoplasma-positive sera cross-reacted with both T. gondii and N. caninum antigens, and one out of 110 Toxoplasma-negative sera reacted with N. caninum antigen by ELISA. By western blot, all 12 sera react...

Objective: Sera from 186 sheep (93 rams and 93ewes) from Tabriz, North-West of Iran were evaluated for antibodies to Toxoplasma gondii using a commercial ELISA kit. Methods: The animals were divided into two age groups (< 2 years, and > 2 years). Results: Antibodies to T. gondii were found in 13 of 186 sheep (6.98%). Infection rate in ewes was higher than rams but this differe...