INTRODUCTION While paraneoplastic syndromes in patients with malignant and metastasizing tumors are common, they are rarely associated with skin tumors showing predominantly local growth patterns. This case report relates to a patient with giant condyloma acuminatum, also called Buschke-Löwenstein tumor, with paraneoplastic hypercalcemia, who was successfully treated with conservative treatment...

tumours of odontogenic origin have been reported in various domestic animals. ameloblastic fibroodontomais a rare tumour derived from odontogenic epithelium and pulpal mesenchyme. plain andformalised sections from masses on the front of the cranial aspect of the jaw and the end of the tongue of acastrated beef cattle from an abattoir was submitted to mt pleasant laboratories, launceston, austra...

Historically it has been shown repeatedly that single high doses of radiation do not allow a therapeutic differential between tumor and critical normal tissues but dose fractionation does. The purpose of conventional dose fractionation is to increase dose to the tumor while preserving normal tissue function. Tumors are generally irradiated with 2Gy dose per fraction delivered daily to a more or...

Tuberculosis (TB), a chronic bacterial disease caused by Mycobacterium tuberculosis , commonly affects the lung but can also affect other parts of body (extrapulmonary tuberculosis, EPT). A rapid diagnosis is essential to initiate specific and effective treatment. Although mycobacterial culture remains gold standard for EPT diagnosis, molecular tools are attracting increasing interest. GeneXper...

This report presents the findings of TIL development from tumour biopsies of patients with bladder cancer. Analysis of tissue sections showed the presence of T cells in intra-epithelial layer in 8 of 12 cases investigated. In a larger group of patients, TILs were established from 7 of 20 cases and expansion of these cells in Interleukin-2 (IL-2) in the presence of conditioned medium (CM) r...

Dear Editor, Giant condyloma acuminate (GCA) fi rst described by Buschke, also known as Buschke-Löwenstein tumour (BLT), is a slow growing, semi malignant neoplasm of the external genitalia and perianal region that has a recurrence tendency.1 Inspite of its histologically benign appearance, BLT clinically behaves in a malignant fashion, destroying adjacent tissues, and is reported as an entity ...