The intestinal epithelial barrier, which is regulated by the actin cytoskeleton, exhibits permeability changes during inflammation. Here we show that activation of the CysLT(1) receptor by the inflammatory mediator leukotriene D(4) (LTD(4)) causes a rapid increase in stress-fibre formation in intestinal epithelial cells. This effect was mimicked by cytotoxic necrotising factor-1 (CNF-1)-induced...

The cultivation of special corns, such as baby corn, has had a positive influence on the economy country. Despite its importance, there is still need for studies aimed at increasing production and planting areas crop. Phytosanitary are particular interest, crops susceptible to series pathogens, Bipolaris maydis, Exserohilum turcicum, Puccinia polysora. use resistant cultivars most effective way...

RhoA/Rho kinases (ROCK) play a critical role in vascular smooth muscle cell (VSMC) actin cytoskeleton organization, differentiation, and function and are implicated in the pathogenesis of cardiovascular disease. We have previously determined that an important step in the regulation of calcification is fetuin-A endocytosis, a process that is dependent on changes in the cytoskeleton, which, in tu...

National science and technology (S&T) systems are often mentioned as a condition for competitiveness of high technology sectors. Therefore, public S&T policies should actively support the development of national S&T systems. In particular in Eastern Europe an active S&T policy is often demanded to support the development of the supposed domestic "high technology potential". This paper shows tha...

BACKGROUND Marek's disease virus (MDV) is an oncovirus that induces lymphoid tumors in susceptible chickens, and may affect the epigenetic stability of the CD4 gene. The purpose of this study was to find the effect of MDV infection on DNA methylation status of the CD4 gene differed between MD-resistant (L63) and -susceptible (L72) chicken lines. METHODS Chickens from each line were divided in...

Tracing dust in small dense molecular cores is a powerful tool to study the conditions required for ices form during prestellar phase. To these environments, five were observed: three with ongoing low-mass star formation (B59, B335, and L483), two starless collapsing (L63 L694-2). Deep images taken infrared JHK bands United Kingdom Infrared Telescope WFCAM (Wide Field Camera) instrument IRAC ch...