Lactobacillus paracasei N1115 is a new strain with probiotic properties isolated from traditional homemade dairy products in Inner Mongolia, China. Here, we report the complete genome sequence of L. paracasei N1115, which shows high similarity to the well-studied probiotic Lactobacillus rhamnosus GG, and 3 structures turned out to be inversions, according to the colinearity analysis of the BLAS...

AIMS The purpose of this study was to investigate the heat-shock response at molecular level in Lactobacillus rhamnosus GG, Bifidobacterium animalis subsp. lactis BB-12 and their heat-tolerant derivatives and to characterize the changes that make the derivatives more robust in terms of heat stress. METHODS AND RESULTS The study strains were exposed for 2 h to a heat-shock treatment, Bif. anim...

Production and manufacturing methods and the food carrier may influence the properties of probiotic strains, and have an impact on the outcome of clinical intervention studies. The aim of the present study was to establish whether the properties of a specific probiotic strain, Lactobacillus rhamnosus GG, may differ depending on the product and source of the strain. In total, fifteen different L...

An L-fucose operon of probiotic Lactobacillus rhamnosus GG involved in 1 adaptation to gastrointestinal conditions 2 3 4 Jimmy E. Becerra, María J. Yebra and Vicente Monedero* 5 6 Laboratory of Lactic Acid Bacteria and Probiotics, Biotechnology Department, Institute of 7 Agrochemistry and Food Technology (IATA-CSIC), Paterna, Valencia, Spain 8 9 10 11 *Corresponding author. 12 E-mail: btcmon@ia...

OBJECTIVE The incidence of nosocomial infections, predominantly gastrointestinal and respiratory, in children in developed countries is high, ranging from 5% to 44%. There is no effective strategy for preventing these infections. The objective of our study was to investigate the role of Lactobacillus GG (LGG) in preventing nosocomial gastrointestinal and respiratory tract infections at a pediat...

Many term and preterm infants are commonly supplemented with probiotics to prevent adverse effects of antibiotic administration and necrotizing enterocolitis and they are believed to be safe. However, the supplementation with Lactobacillus rhamnosus GG has been associated with the development of sepsis with a cause-effect relationship in six newborns and children. In this study, we report two f...

Bu çalışmada ultrason uygulamasının farklı probiyotik laktobasil (Lactobacillus acidophilus, Lactobacillus casei, rhamnosus GG) türlerinin canlılığına etkisini incelenmiştir. Ayrıca, fermentasyon süresine etkisi de saptanmıştır. amaçla süte önce 15 dk süreyle 400 W uygulanmış ve kültür ilavesi sonrasında da 5 100 uygulanarak süresi belirlenmiş elde edilen yoğurt benzeri fermente süt ürününde ba...

Although recent studies have reported that Lactobacillus rhamnosus GG (LGG), the most extensively studied probiotic strain, exerts an anti-hyperglycemic effect on several rodent models, the underlying mechanism remains unclear. In this study, twenty male C57BL/KsJ-db/db (db/db) mice were divided into 2 groups, LGG-treated and control group, which received a daily dose of LGG (1 × 10(8) CFU per ...

We generated a neonatal pig model with human infant gut microbiota (HGM) to study the effect of a probiotic on the composition of the transplanted microbiota following rotavirus vaccination and challenge. All the HGM-transplanted pigs received two doses of an oral attenuated rotavirus vaccine. The gut microbiota of vaccinated pigs were investigated for effects of Lactobacillus rhamnosus GG (LGG...

In evaluating the therapeutic efficacy of gammaglobulin preparations in patients with agammaglobulinemia, opsonic activity of patients' sera in terms of oxygen consumption capacity of normal leukocytes is advocated as a useful index. Although the serum lgG level is a commonly used indicator, its determination alone was found out not always to reflect antibody levels in such sera. The method des...