In fetal rats 5-7 days before birth, the duodenal epithelium is separated from mesenchymal cells by a well-defined basal lamina. By 3-4 days before birth, when small rudimentary villi are first seen, direct contact between epithelial and mesenchymal cells occurs by means of epithelial cell cytoplasmic processes which project through gaps in the basal lamina into the lamina propria. At contact s...

Replication kinetics and invasion characteristics of equine herpesvirus-1 and -3 (EHV-1/-3) in nasal and vaginal mucosae were compared using explants. The explants were cultured during 96 h with little change in viability. The tissues were inoculated with EHV-1 03P37 (neuropathogenic), 97P70 (abortigenic) and EHV-3 04P57, collected at 0, 24, 48 and 72 h post inoculation (pi) and stained for vir...

The histology of the rectal mucosa in 57 men with culturally-proven rectal gonorrhoea is described and the results compared with the findings in biopsies from 57 non-infected men. An acute inflammatory cell infiltration of the rectal mucosa was found in three (5.3%) and two (3.5%) infected and non-infected men respectively. Twenty-one (36.8%) men with rectal gonorrhoea and nine (15.8%) non-infe...

Infiltration of the lamina propria of the mucosa of the small intestine with 'foamy' macrophages (histiocytes) which give a strongly positive cytoplasmic reaction with the periodic acid-Schiff (P.A.S.) stain is considered diagnostic of Whipple's disease (Black-Schaffer, 1949; Chears, Hargrove, Verner, Smith, and Ruffin, 1961; Farnan, 1958; Plummer, Russi, Harris, and Caravati, 1950; Sieracki an...

The cellular infiltrate of the jejunal mucosa has been studied in patients with both treated and untreated adult coeliac disease and dermatitis herpetiformis and serially in treated patients before and after the reintroduction of gluten to the diet. In adult coeliac disease and dermatitis herpetiformis the jejunal mucosa showed similar abnormalities of the cellular infiltrate which was characte...

The thorny headed acanthocephan, Pallisentis nagapurensis infects the intestine of fresh water murrel, Channa striatus. This parasite broughts severe histopathological changes in the intestine includes mucosa and submucosa are completely disrupted, thickened lamina propria, damage of epithelial cells, mucosa folds clumped. The intestinal villi of the mucosa shrinked, infected intestine often en...

an inflammatory cell infiltrate into the diseased tissue with increased numbers of T cells in the mucosa.3 4 Immunophenotyping of T cells has failed to show any gross abnormalities in inflammatory bowel disease: the proportions of CD4+ and CD8+ cells being similar in diseased and normal tissue4-6 and there are no obvious defects in function.7 The use of monoclonal antibodies to markers of T cel...

Day-old chicks are very susceptible to infections with Salmonella enterica subspecies. The gut mucosa is the initial site of host invasion and provides the first line of defense against the bacteria. To study the potential of different S. enterica serovars to invade the gut mucosa and trigger an immune response, day-old chicks were infected orally with Salmonella enterica serovar Enteritidis, S...

Non-major histocompatibility complex-restricted cytotoxicity or natural killer (NK) activity could be detected in all intestinal lamina propria mononuclear cell preparations of histologically normal mucosa from 57 patients with gastrointestinal disease. Similar levels of NK activity were detected among the different disease groups. Within the inflammatory bowel disease patient group, however, C...