PURPOSE Debate on adjunct screening in women with dense breasts has followed legislation requiring that women be informed about their mammographic density and related adjunct imaging. Ultrasound or tomosynthesis can detect breast cancer (BC) in mammography-negative dense breasts, but these modalities have not been directly compared in prospective trials. We conducted a trial of adjunct screenin...

PURPOSE To prospectively assess accuracy of mammography, clinical examination, ultrasonography (US), and magnetic resonance (MR) imaging in preoperative assessment of local extent of breast cancer. MATERIALS AND METHODS Institutional review board approval and informed patient consent were obtained. Results of bilateral mammography, US, and contrast-enhanced MR imaging were analyzed from 111 c...

Breast density is associated with reduced imaging resolution in the detection of breast cancer. A biochemical approach that is not affected by density would provide an important tool to healthcare professionals who are managing women with dense breasts and suspicious imaging findings. Videssa® Breast is a combinatorial proteomic biomarker assay (CPBA), comprised of Serum Protein Biomarkers (SPB...

Abstract Purpose of Review Automated breast ultrasound (ABUS) is a three-dimensional imaging technique, used as supplemental screening tool in women with dense breasts. This review considers the technical aspects, pitfalls, and use ABUS clinical practice, together new developments future perspectives. Recent Findings has been approved USA Europe for asymptomatic breasts addition to mammography....

The rate of male breast cancer has increased in recent years, due to the deficiency of preventive examinations (male mammography). Besides, since male breasts are generally smaller than female breasts, it is essential to monitor the doses received by male breasts, as well as those received by close, healthy and critical organs in order to assess the plan used in this kind of treatment. To do th...

Breast cancer patients with significant comorbidities present reconstructive challenges due to a predictably high complication rate. During expander-based breast reconstruction, human acellular dermal matrix (ADM) is often used to prevent pectoralis muscle retraction, facilitate early expansion, and improve cosmetic outcome. Device infection and chronic seroma have been correlated to the additi...

The incidence of breast cancer in Japan has been gradually increasing (1, 2). Although the age at which women are most susceptible to breast cancer is lower than that for other cancers (3), the 5-year posttreatment survival rate in breast cancer is favorable in comparison to that in many other cancers. Thus, the prognosis of patients with breast cancer is relatively good. Therefore, patients’ p...

PURPOSE To establish a comprehensive proteomic approach for biomarker discovery and validation in breast fluid. EXPERIMENTAL DESIGN A total of 95 specimens from three institutions were used including 10 nipple aspiration fluid (5 stage I/II cancerous breasts and 5 age-matched healthy controls), 42 ductal lavage fluid from 14 patients with unilateral stage I/II cancer (25 from 9 cancerous brea...

OBJECTIVE To analyze the impact of prognostic human epidermal growth factor receptor-2 (HER-2) in invasive breast cancers on the findings of thermography tests. METHODS The study was carried out at the Department of Surgical Oncology and the Department of Pathology, University Clinical Hospital Center, Sisters of Mercy, Zagreb, Croatia, in collaboration with licensed infrared (IR) thermogr...

Multiple clinical studies have demonstrated that the use of screening mammography reduces mortality from breast cancer. 2, 3 The efficacy of mammography depends upon the ability to identify cancers based on the differing absorption of x-rays in cancerous tissue compared to adipose and glandular tissue. In mammography cancers often appear ‘white’, similar to normal glandular tissue, making cance...