The purpose of this study was to evaluate the predictability and stability of laser-assisted subepithelial keratectomy (LASEK) with mitomycin C (MMC) in correction of high myopia (≤-6.0 diopters [D]) as compared to low-to-moderate myopia (>-6.0 D).This is a retrospective, comparative, cohort study which included 43 eyes of 43 consecutive patients who underwent LASEK with MMC in a private hospit...

Excess caveolin-1 has been reported to play a role in age-dependent hyporesponsiveness to growth factors in vitro. Therefore, we hypothesized that caveolin-1-dependent hyporesponsiveness to growth factors in aged corneal epithelial cells might be responsible for delayed wound healing in vivo. To test this hypothesis, we evaluated corneal wound-healing time by vital staining using fluorescein af...

PURPOSE To study the effect of mitomycin C (MMC) on the corneal regrowth after laser-assisted sub-epithelial keratectomy (LASEK). METHODS We performed a prospective, controlled, observer-masked study of 64 consecutive eyes scheduled to undergo LASEK to correct their myopia. The patients were divided into two age-matched groups, with group 1 including 32 eyes in which the ablation depth was ≤ ...

BACKGROUND AND METHODS Myopic photorefractive surgery induces a reduction in central corneal thickness, which may lead to underestimation of intraocular pressure. This retrospective clinical study compared intraocular pressure measurements obtained by Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT-Pascal) in eyes undergoing myopic intralaser-assisted in situ keratomileu...

purpose: to compare the safety, efficacy, predictability, stability and complications of wavefront-guided laser-assisted subepithelial keratectomy (lasek) in low myopia, myopic astigmatism and high myopia correction. methods: in his retrospective study, 416 eyes were divided to 3 groups: 159 eyes with low myopia (lm) and mean refractive spherical equivalent (mrse) of -3.68±1.33 (sd) diopter (d)...

PURPOSE To evaluate the efficacy and safety of laser-assisted subepithelial keratectomy (LASEK) for the treatment of myopia and astigmatism (low, moderate and high). MATERIAL AND METHODS Laser-assisted subepithelial keratectomy was performed by 3 surgeons in 45 eyes using an INPRO Gauss Excimer laser (31 eyes) or a NIDEK EC-5000 Excimer Laser (14 eyes). The mean follow-up is 9 months (3-15 mo...

Purpose: This study was designed to measure binocular function, patient satisfaction and to evaluate postoperative outcomes of presbyopic patients selecting monovision correction either by laser in situ keratomileusis (LASIK) or Laser Assisted Sub-Epithelial Keratomileusis (LASEK). Methods: We carried out a Retrospective chart review of 86 selected patients 40 years and older, treated with refr...

Background – We aimed to evaluate the effectiveness, safety, and patient satisfaction of laser epithelial keratomileusis (LASEK) for myopia in patients with thin cornea. Methods – Seventy-one eyes of 56 patients with myopia of –1.50 to –8.75 diopters (D) and corneal thickness of 451 – 499 microns were enrolled in this prospective clinical study. Slit-lamp examination, manifest refraction, uncor...

OBJECTIVE To determine whether procedure room environmental conditions are associated with outcomes after myopic laser in situ keratomileusis (LASIK) or laser-assisted keratomileusis (LASEK). DESIGN Retrospective chart review. PARTICIPANTS Eight hundred sixty-three eyes of 458 consecutive patients at a university-based academic practice. METHODS We reviewed the medical records of consecut...

The aim of this study was to determine the effect of using 20% alcohol on corneal epithelial tight junctions during laser epithelial keratomileusis (LASEK). Sixty Sprague-Dawley rats were randomly divided into two equal groups. The central area of the rat corneas in one group were demarcated with a 3-mm trephine, treated with 20% alcohol for 45 sec and washed with sterile balanced salt solution...