Prolotherapy is a technique that involves the injection of an irritant, usually a hyperosmolar dextrose solution, typically in the treatment of chronic painful musculoskeletal conditions. Despite its long history and widespread use as a form of complementary therapy, there still are disparities over its optimal indications and injection preparations. There are, however, numerous studies availab...

OBJECTIVE To appraise existing evidence for prolotherapy, polidocanol, autologous whole blood and platelet-rich plasma injection therapies for lateral epicondylosis (LE). DESIGN Systematic review. DATA SOURCES Medline, Embase, CINAHL, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine. SEARCH STRATEGY names and descriptors of the therapies and LE. STUDY SE...

Background:  The primary aim of this study was to determine predictors of missed research appointments in a prospective  andomized placebo injection-controlled trial with evaluations 1 to 3 and 5 to 8 months after enrollment.   Methods:  This study represents a secondary use of data from 104 patients that were enrolled in a prospective randomized  ontrolled trial of dexamethasone versus lidocai...

We welcome the opportunity to respond to the informative letter regarding the terminology of concentric and eccentric. We certainly agree that it is exceedingly important to be as precise and accurate as possible when using these and any scientific terminology. The authors of the letter astutely point out the difference in terminology between movement of a single muscle compared with movement o...

the resistant* of patesa against lateral displacement (le. the stability), was studied tinder a range of conditions in vitro, at a range of knee flexion angles. muscle forces were applied in physiological directions along the separate quadriceps muscles. normal muscle actions with constant tension showed constant patellar stability up to sixty degrees knee flexion, and then a significant increa...