conclusions: this study showed acceptable sensitivity and specificity of qtcd and qtd in comparison to lvmi; it seems that standard ecg can be used for early diagnosis of cardiac involvement in asymptomatic patients with thalassemia major. patients and methods: in a case-control study, 60 patients older than ten years of age with thalassemia major who received regular blood transfusion and iron...

We studied the effects of vigorous rowing training on left ventricular structure and function using M-mode, two-dimensional and Doppler echocardiography in 10 female college rowers. Echocardiographic measurements were performed before and after 20 weeks of rowing training. Diastolic function was also estimated by measuring the isovolumetric relaxation time (IRT), deceleration time (DcT), peak v...

OBJECTIVES Our aim in this study was to determine whether increased left ventricular mass (LVM) is a risk factor for the development of a reduced left ventricular ejection fraction (LVEF). BACKGROUND Prior studies have shown that increased LVM is a risk factor for heart failure but not whether it is a risk factor for a low LVEF. METHODS As part of the Cardiovascular Health Study, a prospect...

Regression of hypertensive left ventricular hypertrophy (LVH) is associated with improved prognosis. The aim of this trial was to compare the effects of irbesartan versus atenolol on LVH in subjects with essential hypertension. Because electrocardiographic and echocardiographic parameters of LVH carry disparate prognostic information, both methods were applied in this trial. In the randomized, ...

Several studies have established that the increase in arterial stiffness (AS) is a cardiovascular risk factor but to date no studies have evaluated in hypertensive patients its prognostic value in comparison with another powerful risk factor, left ventricular mass (LVM) as measured by echocardiography. We prospectively evaluated the prognostic value of AS and LVM in patients with essential hype...

BACKGROUND Previous studies have shown a significantly higher correlation between left ventricular mass index (LVMi) and high-frequency QRS components (HF-QRS) than between LVMi and QRS amplitudes in the standard frequency range in rabbits. The purpose of the present study was to compare ECG measurements from standard and high-frequency ranges with left ventricular mass (LVM) and LVMi determine...

BACKGROUND Polymorphisms in 11-β hydroxysteroid dehydrogenase type 1 (11β-HSD1, encoded by HSD11B1) have been reported to be associated with obesity-related cardiovascular risk factors, such as type II diabetes and hypertension. Left ventricular hypertrophy (LVH) is an independent risk factor for cardiovascular death associated with these factors but has significant additional heritability, the...

Background: The impact of different definitions of left ventricular hypertrophy (LVH) on the assessment of left ventricular (LV) remodeling in predialysis chronic kidney disease (CKD) remains unclear. Methods: Echocardiography was performed on 107 consecutively enrolled patients with different stages of CKD including 36 patients mild CKD (CKD stages 1 and 2) and 71 patients with moderate/severe...

For estimating left ventricular mass (LVM), ECG criteria for left ventricular hypertrophy (LVH) were selected from conventional 12-lead ECGs, orthogonal three-lead ECGs, and multiple-dipole ECGs (MDECG). The three cardiograms were recorded in 139 patients for whom the degree of LVH was independently determined from biplane ventriculograms. Tested ECG criteria included Sokolow-Lyon measurements ...

High blood pressure is the leading cause of left ventricular hypertrophy (LVH); however, not all hypertensive patients develop LVH. Genetic factors are important in the development of LVH. With the use of F2 male rats from spontaneously hypertensive rats and Lewis rats, we performed a study to identify the quantitative trait loci (QTL) that influence left ventricular mass (LVM). Mean arterial p...