Background: Leptin has been implicated in the differentiation and proliferation of hematopoietic cells. Leukemia inhibitory factor (LIF) may play an important role, along with Interleukin-6 (IL-6) and granulocyte colony stimulating factor (G- CSF), in the regulation of early hematopoietic stem cells. The aim of the study was to evaluate serum level of leptin, LIF, and IL-6 in myeloid leukemia p...

obesity is a chronic disease that shows the most serious global health problems .it relates to the body fat .obesity is caused by an imbalance between energy intake and expenditure, this balance is regulated by genetic and environmental interactions. obesity, which is a risk factor for chronic diseases, has become epidemic in the developed countries. resistance to leptin hormone is one of the m...

Abstract Background Idiopathic intracranial hypertension (IIH) is typically seen in females of childbearing period; therefore, it possible that female sex hormones have a pathogenic role IIH. Obesity considered as strong risk factor for IIH, Leptin levels the serum and CSF were found to be positively correlated with anthropological measures obesity. The leptin pathogenesis idiopathic not fully ...

Background Beta-thalassemia is the most common hematology disease in human and leptin is one of the hormone that produce by adiposities cells. The purpose of this study was to investigate the relationship between serum leptin level and thyroid hormones in children with major beta-thalassemia. Materials and Methods This descriptive-cross sectional study was performed on 90 children aged 6-16...

Osteoporosis is a systemic skeletal disease and there is a close relationship between the sympathetic nervous system (SNS) and bone metabolism. Leptin has been shown to regulate bone formation and bone resorption via the SNS. However, the effect of SNS on leptin signaling has not been clearly understood. In the present study, we studied the effect of propranolol on ovariectomy-induced osteoporo...

background leptin and adiponectin are two hormones, which are released from adipocytes in order to control energy expenditure. both hormones are also involved in glucose homeostasis through control of insulin secretion from pancreatic islets. since pdx1, pparγ, and foxm1 play important roles in islets function, it is essential to understand how these genes are regulated in the islets of langerh...

the aim of this study was to investigate the effect of acute swimming stress on plasma corticosterone and leptin levels in female and male rats. thirty- seven adult male (n=20) and female (n=20) sprague dawley rats (200-250 g weight) were used. the leptin and corticosterone levels were measured following swimming stress (10 minutes) or no stress. plasma leptin and corticosterone were measured b...

background beta-thalassemia is the most common hematology disease in human and leptin is one of the hormone that produce by adiposities cells. the purpose of this study was to investigate the relationship between serum leptin level and thyroid hormones in children with major beta-thalassemia. materials and methods this descriptive-cross sectional study was performed on 90 children aged 6-16 yea...