calcium metabolic disorders, such as hypercalcemia is a potentially life-threatening disorder especially when coupled with an already compromised condition. the aim of this study was to determine the prevalence of metabolic calcium disorders in childhood cancers of patients admitted to the pediatric ward of vali-asr hospital from the year 2001-2008. the study was carried out by reviewing hospit...

Herein, we present a rare case of acute myeloid leukemia (AML) with CBFA2T3-rearrangement and the expression megakaryocytic lymphoid markers, highlighting need for high suspicion index in differential diagnosis applying adequate workup to avoid misdiagnosing this entity. CBFA2T3::GLIS2-positive AML is primarily found infants non-down syndrome megakaryoblastic (non-DSAMKL). Flow cytometry immuno...

recent studies have provided evidence that common genetic variations could account for a proportion of leukemia in adult or children. to evaluate the contribution of candidate gene association studies to the understanding of genetic susceptibility to acute lymphoblastic leukemia we conducted a systematic review from published studies. the polymorphisms of genes encoding carcinogen-metabolizing ...

rabies is a fatal neurological infection caused by rabies virus. the deadly rabies virus could enter into human body via the wound that has caused by mammal bite. since rabies is a fatal disease without existing effective treatment, the best way is prevention. the widely examined preventive method for rabies is the use of post exposure rabies vaccination. in this specific case report, the autho...

background: cancer is the third most common cause of death in iran, the leukemia cancer is one of the most important causes of cancer mortality. regarding cancer mortality, data would be important to monitor the program screening effects, earlier diagnosis, demographic data and other prognostic factors. the aim of this study was mortality rates evaluating, then leukemia cancer trends among the ...

evaluation of the factors associated with treatment process of leukemia and comparison with current related approaches in developed countries can present a good indicator to assess the weak and strong points in healthcare system of our country in leukemia treatment. the objective of this research is general and specific description of the challenges and shortcomings in iranian healthcare system...

case presentation we report the case of a 4.5-year-old boy with acute onset bilateral hip and low back pain and inability to walk. examination of passive movements showed that both hips were painful and restricted. conclusions bone pain presenting as localized bilateral irritable hip could be considered as a diagnostic clue related to malignancies. introduction bone pain is common in children. ...

background: since the caregivers of cancer patients have the main and basic role in caring, supporting and monitoring of treatment of these patients, providing their mental health is essential to continue such a care. paying attention to spiritual needs is recognized as an indispensable component of the holistic care in nursing. because of the importance of spirituality in recent years in the f...

Genome-editing systems such as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 technology have uncovered new opportunities to model diseases chronic lymphocytic leukemia. CRISPR/Cas9 is an important means of advancing functional studies Chronic Lymphocytic Leukemia (CLL) through the incorporation, elimination and modification somatic mutations in CLL models.

Background: Leukemia is the most common childhood cancer. This cancer, considering its unknown cause(s), is considered as one of the most important health problems amongst children worldwide. The present study was aimed to determine the relationship between breastfeeding and leukemia in Sistan and Baluchestan province, southeast of Iran. Materials and methods: This case-control study was imple...