نتایج جستجو برای: leukemia lymphocytic chronic b cell

تعداد نتایج: 2734448  

Journal: :Journal of Medical Case Reports 2008
Isrid Sturm Joachim Oertel Stephan Oertel Jörg Westermann Antonio Pezzutto

INTRODUCTION Treatment of chronic lymphocytic leukemia of the B-cell-lineage is strongly based upon clinical staging because of the heterogeneous clinical course of this disease. CASE PRESENTATION We describe a 62-year-old patient with newly diagnosed chronic lymphocytic leukemia of the B-cell-lineage who did not respond to several chemotherapy regimens including chlorambucil, fludarabine and...

Journal: :Haematologica 2011
Sarah E Gibson Steven H Swerdlow Judith A Ferry Urvashi Surti Paola Dal Cin Nancy Lee Harris Robert P Hasserjian

BACKGROUND In the 2008 World Health Organization classification, small lymphocytic lymphoma is defined as a neoplasm with the tissue morphology and immunophenotype of chronic lymphocytic leukemia, but with absence of leukemia. Minimal criteria of tissue involvement to separate small lymphocytic lymphoma from monoclonal B-cell lymphocytosis have not been defined. DESIGN AND METHODS We reviewed...

2005
Emanuela Giombini Giovanni Blandino Ada Sacchi Francesco Lo-Coco Maria Giulia Rizzo

Abbreviations: acute lymphoblastic leukemias, (ALLs); acute myeloid leukemia, (AML); arsenic trioxide, (ATO); B-cell chronic lymphocytic leukemia, (B-CLL); blast crisis, (BC); chronic lymphocytic leukemias, (CLL); CML-Acceleration Phase/Blast Crisis, (CML/AP/BC); CML-Bone Marrow Transplantation patients, (CML-BMT); CML-Chronic Phase patients, (CML/CP); DNA binding domain, (DBD); dominant-negati...

2014
Jennifer Maerki Gordana L. Katava Tatyana Feldman Kar F. Chow Anthony Mato Harry Agress Xiao Y. Yang Andre Goy Pritish K. Bhattacharyya

Background: Coexistence of Chronic lymphocytic lymphoma (CLL) to Acute lymphoblastic leukemia is extremely rare with only a few reported cases [1-5]. Chronic lymphocytic leukemia is a neoplasm of small monomorphic round to irregularly shaped lymphocytes of B-cell lineage. Adverse prognostic factors in CLL include flow cytometric expression of ZAP-70 and CD38 which are surrogate markers for the ...

Journal: :journal of cell and molecular research 0
sasan mohsenzadeh leila najafi zahra amirghofran ahmad reza khosravi

abstract the antineoplastic activities of alcoholic and aqueous extracts of the roots, stems and leaves of isatis campylocarpa an endemic species of the brassicaceae family from iran, investigated on the growth of jurkat as an acute lymphocytic leukemia cell line, k562 as a chronic myelogenous leukemia cell line and fen as a bladder cancer cell line using colorimetric assay. results showed that...

Journal: :Haematologica 2009
Georg Aue Ndegwa Njuguna Xin Tian Susan Soto Thomas Hughes Berengere Vire Keyvan Keyvanfar Federica Gibellini Janet Valdez Carol Boss Leigh Samsel J Philip McCoy Wyndham H Wilson Stefania Pittaluga Adrian Wiestner

BACKGROUND In chronic lymphocytic leukemia lenalidomide causes striking immune activation, possibly leading to clearance of tumor cells. We conducted this study to investigate the mechanism of action of lenalidomide and the basis for its unique toxicities in chronic lymphocytic leukemia. DESIGN AND METHODS Patients with relapsed chronic lymphocytic leukemia were treated with lenalidomide 20 m...

Journal: :acta medica iranica 0
mehrdad hashemi department of genetics, islamic azad university, tehran medical branch, tehran, iran. mehdi nouri long department of medicine, islamic azad university, tehran medical branch, tehran, iran. maliheh entezari department of genetics, islamic azad university, tehran medical branch, tehran, iran. shohreh nafisi department of chemistry, islamic azad university, central tehran branch, tehran, iran. and research institute for islamic and complementary medicine, iran university of medical science, tehran, iran. hossein nowroozii research institute for islamic and complementary medicine, iran university of medical science, tehran, iran.

diet can play a vital role in cancer prevention. nowadays the scientists are looking for food materials which can potentially prevent the cancer occurrence. the purpose of this research is to examine anti-mutagenic and apoptotic effects of apigenin in human lymphoma cells. in present study human chronic lymphocytic leukemia (eheb cell line) were cultured in rpmi 1640 (sigma), supplemented with ...

Journal: :Blood 2005
Eva Mikaelsson Amir Hossein Danesh-Manesh Alfred Lüppert Mahmood Jeddi-Tehrani Mohammad-Reza Rezvany Ramazan Ali Sharifian Reza Safaie Azam Roohi Anders Osterborg Fazel Shokri Håkan Mellstedt Hodjattallah Rabbani

Fibromodulin is an extracellular matrix protein normally produced by collagen-rich tissues; the fibromodulin gene has been found to be the most overexpressed gene in B-cell chronic lymphocytic leukemia. In this study, fibromodulin was expressed at the gene level (reverse transcription-polymerase chain reaction [RT-PCR]) in all patients with B-CLL (n = 75) and in most (5 of 7) patients with mant...

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