BACKGROUND Lifetime risks are often used in communications on cancer to the general public. The most-cited estimate for breast cancer risk (1 in 8 women), however, appears to be outdated. Here we describe the breast cancer burden in the Netherlands over time by means of lifetime and age-conditional risks. The aim is to identify changes in absolute risk of primary breast cancer diagnosis and dea...

PURPOSE To demonstrate a limitation of lifetime radiation-induced cancer risk metrics in the setting of testicular cancer surveillance-in particular, their failure to capture the delayed timing of radiation-induced cancers over the course of a patient's lifetime. MATERIALS AND METHODS Institutional review board approval was obtained for the use of computed tomographic (CT) dosimetry data in t...

BACKGROUND Guidelines from the American Cancer Society recommend annual breast magnetic resonance imaging (MRI) screening for women with a projected lifetime risk of ≥20% based on risk models that use family history. Because MRI screening is costly and has limited specificity, estimates of the numbers of U.S. women with ≥20% breast cancer risk would be useful. METHODS We used data from the 20...

background: exposure to endogenous hormones such as estrogen is known as a lifetime breast cancer (bc) risk factor. polymorphisms in genes that are involved in the steroidogenic process, such as cytochrome p450c17alpha ( cyp17) , affect individuals’ susceptibility to bc. in iran, the highest incident of bc is among young women. this study aimed to find prevalence of single nucleotide polymorphi...

Present study was undertaken to examine the extent of Polycyclic Aromatic Hydrocarbons (PAHs) contamination in neighbourhood lithospheric environment of landfill site situated in eastern outer edge of Kolkata metropolitan city in West Bengal, India, along with its sources identification, spatial distribution and probabilistic cancer risks to residents. The collection and analytical tests were p...

Numerous studies have observed reduced breast cancer risk with increasing levels of physical activity, yet these findings have been inconsistent about optimal times of activity and effect modification by other factors. We investigated the association between recreational and occupational physical activity and breast cancer risk in a population-based case-control study in Massachusetts, New Hamp...

BACKGROUND Existing data suggest that physical activity reduces colon cancer risk, but the association is not consistently observed in women. One potential explanation for this inconsistency is that hormone therapy, which is associated with lower colon cancer risk, acts as a modifier of the physical activity/colon cancer relationship. METHODS Participants in the California Teachers Study (N =...

Introduction: This Study has was  carried out to measure and detect the natural occurred radionuclide content including 226Ra, 232Th and 40K in the  Nile River sediments at various locations in Upper Egypt, from Aswan to El-Minya. Additionally, we determine the absorbed dose rate, the annual effective dose equivalent, and excess lifetime cancer risk also has been calculated. Material and Metho...

Background: Ondo city in Ondo State Nigeria includes Ondo East and West could be described as a research city due to antecedent number of research institutes. Materials and Methods: Dose due to radioactivity content of soil samples from sixteen waste dump sites in Ondo, Southwestern Nigeria was determined using gamma-ray spectrometer in order to evaluate the radiation hazard health profile and ...

Introduction: Nuclear radiation is potentially harmful to humans and soil contamination with radionuclides is the main source of human radiation exposure. These radionuclides can., enter to human body through the food chain. In this study, 34 soil samples were collected from between Arak city and Shazand Power Plant over 20 km length and analyzed. Materials and Methods: The specific activities ...