نتایج جستجو برای: ligand binding

تعداد نتایج: 489309  

Journal: :journal of physical & theoretical chemistry 2006
r. hakimelahi m.a. seyed sadjadi h. aghaie m. aghaie

neutral bidentate n-o type complexe of vo(ii) has been synthesized through condensation of dpenicillamine,(d-h2pen), with bis(acetylacetonate)- oxovanadium(iv),[vo(acac)2], at neutralmedium . the established schiff base(no type) complex was characterized on the basis of ir andmass spectroscopy techniques.besides,d-h2pen binding behavior to[vo(acac)2] has been studiedin thermodynamic viewpoint u...

بخشی, مهین, خزیمه, فائزه, دوست محمدی, محسن, محمدی, المیرا, گلستان‌نژاد, زهرا, گلستان‌نژاد, محمدرضا, گوانجی, شاهین, یوسف شاهی, هژیر,

Background: Protective antigen of anthrax toxin, after touching the cell receptors, plays an important role in the pathogenesis of toxin. The purpose of this study was to investigate the interaction of anthrax toxin protective antigen and four great combination propolis included caffeic acid, benzyl caffeate, cinnamic acid and kaempferol using the softwares and bioinformatics web servers. ...

Journal: :Journal of Biological Chemistry 2000

Journal: :Acta Crystallographica Section A Foundations of Crystallography 2008

Journal: :iranian journal of pharmaceutical research 0
hoda abolhasani tabriz university of medical sciences, tabriz, iran afshin zarghi shahid beheshti university of medical sciences, tehran, iran maryam hamzeh-mivehroud tabriz university of medical sciences, tabriz, iran ali akbar alizadeh tabriz university of medical sciences, tabriz, iran javid shahbazi mojarrad tabriz university of medical sciences siavoush dastmalchi tabriz university of medical sciences, tabriz, iran

interference with microtubule polymerization results in cell cycle arrest leading to cell death. colchicine is a well-known microtubule polymerization inhibitor which does so by binding to a specific site on tubulin. a set of 3',4'-bis (substituted phenyl)-4'h-spiro[indene-2,5'-isoxazol]-1(3h)-one derivatives with known antiproliferative activities were evaluated for their t...

Journal: :Journal of molecular modeling 2007
Michal Brylinski Marek Kochanczyk Elzbieta Broniatowska Irena Roterman

Knowledge-based models for protein folding assume that the early-stage structural form of a polypeptide is determined by the backbone conformation, followed by hydrophobic collapse. Side chain-side chain interactions, mostly of hydrophobic character, lead to the formation of the hydrophobic core, which seems to stabilize the structure of the protein in its natural environment. The fuzzy-oil-dro...

2010
Andreas Boland Felix Tritschler Susanne Heimstädt Elisa Izaurralde Oliver Weichenrieder

Argonaute (AGO) proteins are core components of RNA-induced silencing complexes and have essential roles in RNA-mediated gene silencing. They are characterized by a bilobal architecture, consisting of one lobe containing the amino-terminal and PAZ domains and another containing the MID and PIWI domains. Except for the PAZ domain, structural information on eukaryotic AGO domains is not yet avail...

Journal: :FEBS Letters 2021

Substrate-binding proteins (SBPs) mediate ligand translocation and have been classified into seven clusters (A-G). Although the substrate specificities of these are known to some extent, their ligand-binding mechanism(s) remain(s) incompletely understood. In this study, list SBPs belonging different was updated (764 SBPs) compared previously reported study (504 SBPs). Furthermore, a new cluster...

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