BACKGROUND Removal of mercury from aqueous environment has been highly regarded in recent years and different methods have been tested for this purpose. One of the most effective ways for mercury ions (Hg(+2)) removal is the use of modified nano porous compounds. Hence, in this work a new physical modification of mesoporous silica (SBA-15) with 1, 3, 5 (Trithiane) as modifier ligand and its app...

Several forms of macroscopic N-methyl-D-aspartate (NMDA) receptor desensitization affect the amplitude and duration of postsynaptic responses. In addition to its functional significance, desensitization provides one means to examine the conformational coupling of ligand binding to channel gating. Segments flanking the ligand binding domain in the extracellular N terminus of the NMDA receptor NR...

PERSPECTIVES AND SUMMARY .............................................................. 615 HISTORY ............................................................................................... 616 INDIVIDUAL G PROTEINS: FUNCTIONS AND MOLECULAR ENTITIES .......... 617 Criteria .for Involvement of a G Protein ..................................................... 618 Functions Regulated by G Pr...

A Zn-based, mixed-ligand (pillared paddlewheel), metal-organic framework (MOF) has been covalently and quantitatively decorated with free carboxylic acids to demonstrate the utility of covalent post-synthesis modification in the construction of otherwise inaccessible carboxy-functionalized MOFs.

fac,fac-[Re(I)(CO)3]-complexes of new κ(3)N-tridentate ligands were synthesized and characterized by various analytical techniques including XRD. The regulation of electronic properties of the complexes upon ligand modification is discussed.

This paper describes the fabrication and surface modification of gold microelectrode array structures. The modification is done by continuous cycling of the electrode array in a pH 12 buffer solution containing 8.01 mmol L−1 5,10,15,20-tetrakis-(4-sulphonatophenyl)porphyrin tetrasodium salt (H2TSPor). Incorporation of gold ions in the ligand during the potential cycling of the gold electrode is...

Previously we have shown that prenatal moderate arsenic exposure (50 ppb) disrupts glucocorticoid receptor (GR) programming and that these changes continue into adolescence in males. However, it was not clear what the molecular mechanisms were promoting these GR programming changes or if these changes occurred in arsenic-exposed females. In the present studies, we assessed the effects of arseni...

Amine-tagged defective Ni-MOF-74 was prepared by solvothermal synthesis using aminosalicylic acid as a functionalized fragmented ligand, described Seung Bin Baek, Myoung Soo Lah et al. in their Communication on page 9296. The covalent post-synthetic modification and subsequent metalation with palladium(II) ions affords palladium(II)-incorporated catalyst, which exhibits highly efficient, size-s...

The glucocorticoid receptor (GR) is a member of the nuclear hormone receptor superfamily of ligand-activated transcription factors. In contrast to many other nuclear receptors, GR is thought to be exclusively cytoplasmic in quiescent cells, and only translocate to the nucleus on ligand binding. We now demonstrate significant nuclear GR in the absence of ligand, which requires nuclear localisati...