نتایج جستجو برای: like receptor 7 and 8

تعداد نتایج: 17160222  

2017
Anushree Seth Hyunseung Lee Mi Young Cho Cheongsoo Park Sovannarith Korm Joo-Yong Lee Inpyo Choi Yong Taik Lim Kwan Soo Hong

This study evaluates the effect of combination of two different treatment regimens for solid tumor therapy: vasculature targeting agent and immune-stimulation. Poly lactide-co-glycolide (PLGA) nanoparticles were synthesized for intracellular delivery of Toll-like receptor (TLR) 7/8 agonist-gardiquimod. Spherical and mono-disperse gardiquimod encapsulated PLGA nanoparticles (Gardi-PLGA), approxi...

Journal: :Science 2004
Florian Heil Hiroaki Hemmi Hubertus Hochrein Franziska Ampenberger Carsten Kirschning Shizuo Akira Grayson Lipford Hermann Wagner Stefan Bauer

Double-stranded ribonucleic acid (dsRNA) serves as a danger signal associated with viral infection and leads to stimulation of innate immune cells. In contrast, the immunostimulatory potential of single-stranded RNA (ssRNA) is poorly understood and innate immune receptors for ssRNA are unknown. We report that guanosine (G)- and uridine (U)-rich ssRNA oligonucleotides derived from human immunode...

Journal: :American Journal of Respiratory and Critical Care Medicine 2013

Journal: :Journal of the American Society of Nephrology 2005

Journal: :The Journal of the Society of Chemical Industry, Japan 1953

Ali-Akbar Salari Jalal Solati, Laleh Fatehi Gharehlar Parichehr Yaghmaei Shahrbanoo Oryan,

Objective(s) There is well documented evidence for the increase in widespread use of complementary and alternative medicine in the treatment of physical and psychiatric symptoms and disorders within the populations. In the present study, we investigated the influence of Vitex agnus-castus (vitex) on anxiety-like behaviors of rats. Materials and Methods Elevated plus maze which is one of the ...

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