During spinal cord development, the LIM domains of the LIM homeodomain factor Lhx3 bind to either the LIM cofactor nuclear LIM interactor (NLI) or another LIM homeodomain factor, Isl1, assembling the tetrameric V2 interneuron-specifying Lhx3 complex (2NLI:2Lhx3) or the hexameric motor neuron-specifying Isl1-Lhx3 complex (2NLI:2Isl1:2Lhx3). However, the detailed molecular basis by which the Lhx3...

The mechanisms that regulate the development of the amygdaloid complex are as yet poorly understood. Here, we show that in the absence of the LIM-homeodomain (LIM-HD) gene Lhx2, a particular amygdaloid nucleus, the nucleus of the lateral olfactory tract (nLOT), is selectively disrupted. LIM family members are well suited for multiple roles in the development of complex structures because they p...

In this paper we deal with the relation lim α lim α X = lim α X for a subset X of G, where G is an -group and α is a sequential convergence on G.

Let un sup(ak )∞ k n and vn sup(bk ) ∞ k n be suprema. Then the following obvious relation ak ≤ un and bk ≤ vn , ∀k ≥ n ⇒ ak + bk ≤ un + vn , ∀k ≥ n shows that, upon taking the supremum over all k with k ≥ n, we get sup(ak + bk )∞ k n ≤ un + vn . This shows that for any n ≥ m, we get lim sup k→∞ (ak + bk ) inf j: j≥m sup(ak + bk )∞ k j ≤ sup(ak + bk ) ∞ k n ≤ un + vn Since we know that (un )∞ n...

Hyun-Joo Lim*, Hyun Jong Kim, Ji Hwan Lee, Dong Lim, Jun Kyu Son, Eun-Tae Gulwon Jang and Dong-Hyeon Kim. Journal of Animal Reproduction Biotechnology 2021;36:35-44. https://doi.org/10.12750/JARB.36.1.35

LIM kinases are common downstream effectors of several signalization pathways and function as a signaling node that controls cytoskeleton dynamics through the phosphorylation of the cofilin family proteins. These last 10 years, several reports indicate that the functions of LIM kinases are more extended than initially described and, specifically, that LIM kinases also control microtubule dynami...

The LIM domain-binding protein Ldb1 is an essential cofactor of LIM-homeodomain (LIM-HD) and LIM-only (LMO) proteins in development. The stoichiometry of Ldb1, LIM-HD, and LMO proteins is tightly controlled in the cell and is likely a critical determinant of their biological actions. Single-stranded DNA-binding proteins (SSBPs) were recently shown to interact with Ldb1 and are also important in...

Concentrations of 3-chlorophenol and 4-chlorophenol below their minimal inhibitory concentrations were found to increase the permeability of Pseudomonas aeruginosa cells to protons. Levels of such activity were assessed in suspensions of cells prepared from chemostat-grown cultures, limited by either magnesium (Mg-lim) or glucose (G-lim), with the use of five growth rates. Drug concentrations r...