silymarin is a mixture of flavonolignans from the seeds of silybum marianum (l.) gaertner,containing silybinin, isosilybinin, silydianin, silychristin and the dihydroflavonol of taxifolin. flavonolignancomponents are largely responsible for the medical benefits attributed to silymarin. the aim of this researchwas to study the variations in composition and content of flavonolignans of silymarin ...

background: the effective therapeutic dose of pralidoxime methylsulphate for organophosphate (op) poisoning is necessary to be clarified. this study was designed to comparatively assess the blood level of pralidoxime (bpl) and clinical outcomes in op poisoned patients treated with intermittent dosing and patients treated with continuous infusion. methods: this was a prospective, open labelled, ...

background and objectives:drimia maritima (l.) stearn also known as squill is a medicinally important plant that has been used for various ailments such as dropsy, respiratory disorders, jaundice and epilepsy from ancient times. proscillaridin a is identified as one of the most effective compounds in the plant with remarkable pharmacological features including efficacy against congestive heart ...

background : rhoptries are unique secretory/excretory organelles that are found exclusively in the apicomplexa, and their contents are discharged at the time of invasion and are critical in the establishment of productive infection. several rhoptry proteins have been identified in toxoplasma gondii , plasmodium falciparum and neospora caninum and have been linked not only with the parasites’ ad...

abstract        background and objective: measurement of amino acids is an important tool for metabolic studies and evaluation of patients’ clinical condition. the aim of this study was to analyze the plasma amino acids using reverse phase high performance liquid chromatography techniques (rp-hplc) with pre-column derivatization by o-phthalaldehyde (opa) in combination with 3- mercaptopropionic...

a high performance liquid chromatography method was studied for determination of 18 ?-glycyrrhetinic acid in glycyrrhiza glabra l. (licorice) extract. the operating condition were c-18 reversed phase column (vp-ods, (250×4.6 mm, 5 mm)) at room temperature, acetonitril/phosphoric acid (3/1) as mobile phase, at flow rate of 0.6ml/min (0-8min), 0.4ml/min (8-20min) and uv detection at 230 nm. the r...

this study propose a new analytical protocol for the determination of benzene, xylene, toluene and styrene in water samples using homogeneous liquid-liquid microextraction via flotation assistance (hllme-fa) technique followed by gas chromatography-mass spectrometry (gc-ms). in this research, a special extraction cell was designed to facilitate collection of the low-density solvent extraction. ...

introduction: the mechanism of action and metabolism of clozapine, a complex drug used in psychopharmacology, is not completely understood. the effects of this compound in human body are related to some interactions with serotonin and dopamine neurotransmitter receptors. to further elucidate the mechanism of action and to support ongoing drug metabolism studies, [14c] clozapine with suitable ra...

Preparative HPLC 5}30 '20 2}20 0.01}1 High purity solvent required Higher resolution See also: II/Chromatography: Countercurrent Chromatography and High-Speed Countercurrent Chromatography: Instrumentation. Chromatography: Liquid: Countercurrent Liquid Chromatography. III/Alkaloids: Gas Chromatography; High-Speed Countercurrent Chromatography; Liquid Chromatography; Thin-Layer (Planar) Chromato...