Primary carnitine deficiency (PCD) is a rare autosomal recessive disorder, caused by deficiency in the plasma membrane carnitine transporter. In this report, we aimed to describe the diagnosis and treatment of 12 PCD patients. Blood spots were collected from the children, and analysed using liquid chromatography-mass spectrometry (LC-MS). Newborns and children who had repeated lower dried blood...

The aim of this study is to evaluate the bioactive compounds in the ethanolic leaf extract of Azima tetracantha by using Gas chromatographyMass Spectrometry (GCMS). Azima tetracantha leaves were collected from Ariyalur District, Tamil Nadu. The dried leaf powder was extracted with the solvent ethanol by using Soxhlet apparatus. One microlitre of the extract was subjected for analysis by GCMS to...

Background: Pergularia tomentosa L. has several traditional uses and biological activities which need to be more investigated. Objective: In this study, some ecological and phytochemical properties of Pergularia tomentosa were assessed. The flavonoids and cardenolides in the aqueous extract of leaves were identified with LCMS techniques. Methods: Some quantity characteristics of P. tomentosa...

This study aims to determine the chemical and physical composition antibacterial activity of glasswort. Soxhlet extraction S. europaea was performed using Hexane analyzed by Gas chromatographymass spectrometry. Alpha-tocopherol content analysed Liquid chromatography with tandem mass The elemental analysis investigated inductively coupled plasma crystallographic texture powder samples were deter...

Sialic acids have been found to mask antigens, receptors and other recognition sites on molecules and cells. This has been investigated best with hepatocyte and macrophage lectins which recognize 13-galactose and N-acetyl-13-galactosamine residues on molecules and cells exposed by sialidase treatment. The lectin on macrophages leads to the binding and phagocytosis of erythrocytes after the enzy...

a simple, rapid and efficient dispersive liquid–liquid microextraction by use of ionic liquid (il-dllme)method, followed by flame atomic absorption spectrometry (faas) was developed for the preconcentrationand determination of palladium in water samples. in this method, an appropriate mixture of acetone and octylmethyl imidazolium hexafluorophosphate was injected rapidly into the aqueous sample...

The investigation into whether Mars contains signatures of past or present life is of great interest to science and society. Amino acids and nucleobases are compounds that are essential for all known life on Earth and are excellent target molecules in the search for potential Martian biomarkers or prebiotic chemistry. Martian meteorites represent the only samples from Mars that can be studied d...

LCMS/MS method was used (ESI Source) to determine the concentration of Paclitaxel coated drug eluting stents (316 LVM). LCMS/MS has proved to be a powerful research tool due to its sensitivity, high selectivity, and high throughput efficiency to determine drug concentration of the sample. The elution kinetics was carried out on flow through dissolution apparatus-USP-4 (Sotax) .The samples were ...