Background and Aims: Hepatocellular carcinoma (HCC) is one of the most important common cancers in the world. The main etiology of this cancer in developing and third world countries is due to the infection with hepatitis B and C viruses. Hepatitis B and C viruses (HCV) would both cause liver cancer but the incidence of the disease in relation to the age and gender has not been determined. The ...

Hepatocellular carcinoma (HCC) accounts for 85% of primary liver cancer, the third most common cause cancer-related deaths worldwide. Its incidence has been increasing in both men and women. In Western countries, high-calorie diets, mainly rich carbohydrates such as fructose, represent a significant concern due to their repercussions on population’s health. A high-fructose diet is related devel...

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and second leading cause of cancer related death worldwide...

Increased second primary liver cancer risk in young breast patients undergoing radiotherapy and chemotherapy: a nationwide population-based study

A series of tertiary sulphonamide derivatives were synthesised and evaluated for their antiproliferative activity against liver cancer cell lines (SNU-475, HepG-2, Bel-7402). Among these sulphonamides, compound 17a displayed the best anti-liver Bel-7402 cells with an IC50 value 0.32 μM. Compound could effectively inhibit tubulin polymerisation 1.27 Meanwhile, it selectively suppressed LSD1 63 n...

This article refers to:RETRACTED ARTICLE: Structural characterization and anti-liver cancer activity of a Cu(II)-based coordination polymer

the incidence of drug induced liver injury (dili) is about 1/1000 to 1/10000 among patients who receive therapeutic drug doses. drug induced hepatotoxicity is a major cause of acute and chronic liver disease. the severity of liver damage ranges from nonspecific changes in liver structure to acute liver failure, cirrhosis and liver cancer. some common agents that can cause liver injury are aceta...

context studies on experimental animals have shown liver is a common target of chemical carcinogens; this might suggest that occupational exposure to chemicals is another risk factor for hcc. however, the relationship between occupation and liver cancer has not been extensively studied, with the exception of the known association between vinyl chloride and angiosarcoma of the liver. evidence ac...

In recent decades, gut microbiota have received emerging attention regarding their integral role in chronic liver disease progression, given the anatomic connection and gut–liver axis. Emerging evidence has indicated a complex link between hepatocellular carcinoma. This review explores pathophysiological crosstalk dysbiosis hepatocarcinogenesis. The metabolic immunologic effects mediated by gut...

Background: Complementary foods are given to infants when breast milk alone becomes insufficient in meeting their nutritional needs. The major objective of this study was to assess the prevalence of Aflatoxins (AFs) in Weanimix complementary foods purchased from shops in Accra (Ghana), and to estimate risk of liver cancer development in infants.  Methods: In total, 32 samples of Weanimix were ...