Lumbar disc herniation is one of the most common medical and surgical problems all over the world. The vast majority of lumbosacral radiculopathies are caused by paracentral herniation. However, Hood reported that far lateral lumbar disc herniation (FLLDH) accounts for 2.8 – 10% of all disc herniations. Over 75% of FLLDHs occur at the L3 –L4 and L4 – L5 levels. In addition, FLLDH presents a cli...

The traditional view that the etiology of lumbar disc herniation is primarily due to age, gender, occupation, smoking and exposure to vehicular vibration dominated much of the last century. Recent research indicates that heredity may be largely responsible for the degeneration as well as herniation of intervertebral discs. Since 1998, genetic influences have been confirmed by the identification...

Intradural lumbar disc herniation is a rare pathological entity. The pathogenesis of intradural lumbar disc herniation is not known clearly. Intradural disc herniations usually occurred at the L4-L5 levels but have also been reported at other levels. However, intradural disc herniation at L5-S1 is quite rare. There are approximately nine reports in the English literature of intraradicular disc ...

background: ninety percent of all people sometimes during their lives experience low back pain, and 30-40% develops radicular leg pain with the sciatica characteristics. although for clinical diagnosis of lumbar disc herniation (ldh) straight leg raising (slr) test in 85-90% of cases indicates ldh, but in our practice with ldh patients this test is frequently negative despite radicular leg pain...

BACKGROUND We designed an easy posterolateral transforaminal endoscopic decompression technique, termed PTES, for radiculopathy secondary to lumbar disc herniation. The purpose of the study is to describe the technique of PTES and evaluate the efficacy and safety for treatment of lumbar disc herniation including primary herniation, reherniation, intracanal herniation, and extracanal herniation ...

Background Lumbar disc herniation is a major cause of radicular pain, but the underlying mechanisms remain largely unknown. Spinal activation of src-family kinases are involved in the development of chronic pain from nerve injury, inflammation, and cancer. In the present study, the role of src-family kinases activation in lumbar disc herniation-induced radicular pain was investigated. Results L...

Symptoms from lumbar disc herniation are common in the general population. Many discs heal spontaneously and the patient’s symptoms cease. When people have severe pain and sciatica, the recommendation is to start with physiotherapy treatment and pain medication for at least six to eight weeks before surgery is considered. There is, however, limited evidence relating to the effects of physiother...

The association of the activation-inducible tumor necrosis factor receptor and ligand with lumbar disc hermiation. Purpose: Herniated nucleus pulposus fragments are recognized by the immune system as a foreign-body, which results in an autoimmune reaction. Human activation-inducible tumor necrosis factor receptor (AITR) and its ligand, AITRL, are important costimulatory molecules in the pathoge...

The parents of sixty-three patients who were less than twenty-one years old and who had operatively confirmed herniation of a lumbar disc were interviewed regarding a history of sever back pain, sciatica, and herniated disc, to determine whether aggregation of herniation of a lumbar disc occurs in families of patients in this young age-group. The parents of sixty-three additional patients who h...

Objective. The aim of this study was to evaluate the efficacy of a three-dimensional (3D) turbo spin-echo (TSE) sequence for determining lumbar disc protrusions, and to compare the findings with those of conventional two-dimensional (2D) TSE sequences and reveal the interobserver and intermethod agreements of both sequences. Methods. A total of 127 discs from 84 patients were evaluated by three...