malignant fibrous histiocytoma (mfh) is the most common soft-tissue sarcoma which predominantly surfaces in the retro-peritoneum and extremity. mfh of lung is a very rare condition. the diagnosis is essentially through histologic examination. however, the invasion of the chest wall or other organs might help establish the malignant nature.we report a case of a 77-year-old man who had been prese...

background: trinitrotoluene (tnt) is one of the most well-known and oldest explosive agents. in the recent decade, bioenvironmental, biochemical, and biological effects of tnt exposure have been more in the spotlight. in this study, we aimed to evaluate spirometric parameters in workers of a tnt factory exposed to tnt and other related fumes and dusts compared with the unexposed controls. metho...

introduction: chronic obstructive pulmonary disease (copd) secondary to sulfur mustard exposure, known as mustard lung, is an important late pulmonary complication. the bode (body mass index, obstruction, dyspnea, and exercise) index has been established as a valuable tool for determining the adverse consequences of copd. the aim of this study was to evaluate the role of the bode index in patie...

background: lung cancer is one of the fatal cancers in iran while 12% of the mortalities are related to this cancer in the country. this active hospital-based study was undertaken to determine the occurrence of lung cancer in fars province, southern iran. methods: data including face-to-face interview with patients and a survey of their medical and demographic records in relation to all invasiv...

context worldwide prevalence of respiratory diseases, suffering from such diseases, and heavy cost of treatment, which all may result from lack of etiological understanding of these diseases in modern medicine, were the main factors to conduct the current study. in the present study, the causes and symptoms of asthma were evaluated and compared with those of some other respiratory diseases. ira...

cisplatin-based chemotherapy is the standard treatment for advanced non-small cell lung cancer (nsclc). many novel drugs have been used in combination with cisplatin in this setting. of these drugs, gemcitabine is reported to have a high response rate and acceptable toxicity. the aim of this study was to evaluate the efficacy and safety of gemcitabine and cisplatin combination. twentythree pati...

biomolecular behavior of tumor cells has become attractive to investigators. p53 as an oncosuppresor gene has been core of various studies and ki67 is a nuclear protein involved in proliferation process. stopping of onco-suppressor function theoretically allows proliferative system to get out of any control. in this case-control study we evaluated 50 patients with non small cell lung cancer, co...

cadmium has been known to be harmful to human health, mainly via contaminated drinking water, food supplies, tobacco and industrial pollutants. the aim of this study was to determine the ability of cadmium chloride (cdcl 2 ) to cause cell death in the human lung carcinoma cell line (calu-6). the cells were grown in rpmi-1640 medium supplemented with 10% fcs, penicillin/streptomycin (100 u/ml, 1...

lung contusion is an entity involving injury to the alveolar capillaries, without any tear or cut in the lung tissue. this results in accumulation of blood and other fluids within the lung tissue. the excess fluid interferes with gas exchange leading to hypoxia. the pathophysiology of lung contusion includes ventilation/perfusion mismatching, increased intrapulmonary shunting, increased lung wa...