A copper-catalyzed regioselective and stereospecific aminoboration of vinylsilanes with bis(pinacolato)diboron (pinB-Bpin) and hydroxylamines has been developed. In the presence of a CuCl/MeO-dppbz catalyst, the boryl group and amino group are incorporated at the β position and α position, respectively, and the corresponding β-boryl-α-aminosilanes are obtained with good diastereoselectivity. Th...

New Rb-Sr, (146,147)Sm-(142,143)Nd and Lu-Hf isotopic analyses of Mg-suite lunar crustal rocks 67667, 76335, 77215 and 78238, including an internal isochron for norite 77215, were undertaken to better define the time and duration of lunar crust formation and the history of the source materials of the Mg-suite. Isochron ages determined in this study for 77215 are: Rb-Sr=4450±270 Ma, (147)Sm-(143...

We present a sarcoma patient with a tumor reduction of more than 50% in lung metastasis after 2 single courses of the investigational medical product Lutathera (Lu-DOTA0-Tyr3-octreotate). She was resistant to more than 6 lines of therapy including all the available active drugs in soft tissue sarcomas. The high expression of somatostatin receptors was shown by microarrays and Octreoscan. The ov...

Advertising is an area that is covered by many researches, however, over-the-counter reactions to this important marketing tool has not yet been touched. This article present an exploratory study on this market segment as it respond to the marketing mix involved in the launching of an over-the-counter brand originally successful in the ethical market. The author found that advertising passes tw...

I I 10 10 10 SO t l 70 10 «0 190 110 110 1 CCCAATCAfi ItACTTIIAT CCIMC1CAC SiUl l t tC! ACUIKTCC TIAAlACATI C1IUIIA1C ttlATAITIT AtTTCICTAA AAIATI1AII AtCAAATIU TCKTAACAC i n luccuice ucctititt icittt i i i i CCAHKAAA CAIHCCIAA TACCAIAIAT IAIAAAAAIT TJUTIAAH I I I I I I C I A I internet itcttcicc* ACAAATIIK 111 (1CCCCI1CI ITAITT1CIT UIACIITAA AAKCIUCA ACACtAKAT CTITAICIII KCAACACCT KIACCICCA CA...

Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 Å resolution Parthasarathy Sampathkumar,* Frances Lu, Xun Zhao, Zhenzhen Li, Jeremiah Gilmore, Kevin Bain, Marc E. Rutter, Tarun Gheyi, Kenneth D. Schwinn, Jeffrey B. Bonanno, Ursula Pieper, J. Eduardo Fajardo, Andras Fiser, Steven C. Almo, Subramanyam Swaminathan, Mark R. Chance, David Baker, Shane Atwell, Devon A...

Abstract A simple sublimation technology for the lutetium and ytterbium separation was proposed, which already at stage of preliminary experiments showed effectiveness: (a) completeness Yb resulted in short-term thermal annealing is least 98%, distilled product completely free from 177 Lu, no additional preparation repeated irradiation required ; (b) traditional ion-exchange chromatography can ...

A new BIPHEP-type ligand with phenyl groups at the 3,30-positions, o-Ph-MeO-BIPHEP 3 was prepared. This ligand afforded excellent enantioselectivities when used in the Rh-catalyzed asymmetric hydrogenation of a-dehydroamino acid derivatives. The strong influence of o-phenyl groups of the ligand on the enantioselectivities of the reaction has been demonstrated by a comparison with its parent lig...

Let f(z) = ∑∞ n=1 λf (n)e 2πinz ∈ S k (Γ0(N)) be a newform of even weight k ≥ 2 on Γ0(N) without complex multiplication. Let P denote the set of all primes. We prove that the sequence {λf (p)}p∈P does not satisfy Benford’s Law in any base b ≥ 2. However, given a base b ≥ 2 and a string of digits S in base b, the set Aλf (b, S) := {p prime : the first digits of λf (p) in base b are given by S} h...

We find a different approach to define convex functions in the subRiemannian setting. A function on a sub-Riemannian manifold is nonholonomically geodesic convex if its restriction to any nonholonomic (straightest) geodesic is convex. In the case of Carnot groups, this definition coincides with that by Danniell-Garofalo-Nieuhn (equivalent to that by Lu-Manfredi-Stroffolini). Nonholonomic geodes...