Serum neutralizing antibody and influenza B-specific lymphocyte blast transformation responses were measured in 110 adults and children after an influenza B outbreak. Serum neutralizing antibody and lymphocyte blast transformation responses were seen in 67 to 75% of adults and children recently infected (less than 1 year), but significant lymphocyte blast transformation responses were seen in o...

Current techniques for lymphocyte transformation are evaluated and criticised. A simple technique, designed to meet these criticisms, is described in detail, with particular reference to lymphocyte separation and scoring methods.

Cell-mediated immune reactions delayed dermal hypersensitivity, lymphocyte transformation, and macrophage migration inhibitory factor production were investigated in the ferret. Ferrets immunized with streptokinase in complete Freund's adjuvant had skin test responses characterized by induration with little erythema; skin test biopsies showed mononuclear cell infiltration. In vitro transformati...