نتایج جستجو برای: lyplal1

تعداد نتایج: 42  

2017
Do Kyoon Kim Anna Okula Basile Lisa Bang Emrin Horgusluoglu SeungGeun Lee Marylyn D. Ritchie Andrew J. Saykin Kwangsik Nho

BACKGROUND Rapid advancement of next generation sequencing technologies such as whole genome sequencing (WGS) has facilitated the search for genetic factors that influence disease risk in the field of human genetics. To identify rare variants associated with human diseases or traits, an efficient genome-wide binning approach is needed. In this study we developed a novel biological knowledge-bas...

2012
Caroline S. Fox Yongmei Liu Charles C. White Mary Feitosa Albert V. Smith Nancy Heard-Costa Kurt Lohman Andrew D. Johnson Meredith C. Foster Danielle M. Greenawalt Paula Griffin Jinghong Ding Anne B. Newman Fran Tylavsky Iva Miljkovic Stephen B. Kritchevsky Lenore Launer Melissa Garcia Gudny Eiriksdottir J. Jeffrey Carr Vilmunder Gudnason Tamara B. Harris L. Adrienne Cupples Ingrid B. Borecki

Body fat distribution, particularly centralized obesity, is associated with metabolic risk above and beyond total adiposity. We performed genome-wide association of abdominal adipose depots quantified using computed tomography (CT) to uncover novel loci for body fat distribution among participants of European ancestry. Subcutaneous and visceral fat were quantified in 5,560 women and 4,997 men f...

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