Osteosarcoma (osteogenic sarcoma: OS) is the most common primary malignant bone tumor of long bones, whereas primary osteosarcoma of chest wall, especially in sternum, is extremely rare. We report a 57-year-old man with an immobile slow growing mass located in the middle of the sternum. The patient had no significant pain or tenderness and the past medical history was not remarkable. CT-scan sh...

Objective: Patella is a sesamoid bone which develops in the quadriceps tendon. It is an uncommon site for neoplasms. The most common primary tumors which involve patella are benign. These include chondroblastoma, giant cell tumor (GCT) and aneurysmal bone cyst. Malignant lesions are less common in patella. These encompass metastasis, osteosarcoma and hemangioendothelioma. The most common compla...

OBJECTIVE The present study was done to find out the frequency of malignant tumors of bone and to categorize the prevalence of various histological types of osseous malignancies with respect to age, sex and site of origin. SETTING This study included consecutive cases of malignant bone tumors, which were diagnosed in the department of pathology at the Aga Khan University Hospital, Karachi dur...

background: understanding the differences in genetics of malignancies is crucial for therapeutic decisions. this systematic review was conducted to evaluate the current evidence on genetics of bone tumors in the context of pediatric cancer. material and methods: we performed a systematic review of the literature published on genetics of pediatrics bone tumors, using pubmed, google scholar, scie...

Objective: The present study was done to find out the frequency of malignant tumors of bone and to categorize the prevelence of various histological types of osseous malignancies with respect to age, sex and site of origin. Setting: This study included consecutive cases of malignant bone tumors, which were diagnosed in the department of pathology at the Aga Khan University Hospital, Karachi dur...

Osteosarcoma is a malignant bone tumor that usually affects children and adolescents. Early detection of osteosarcoma tumors increases the likelihood successful therapy. Manual identification requires highly skilled doctors. In this study, we attempt to create model automatically diagnose into three categories; non-tumor, viable-tumor, tumor. The suggested methodology can help medical professio...

osteosarcoma (os) is a malignant mesenchymal tumor, which rarely occurs in the maxilla. although variable histologic and radiographic features of os have been reported previously, in the majority of the cases painful swelling of the jaw is mentioned as the first clinical presentation. furthermore, early diagnosis and wide surgical resection of the tumor are the most important determinant factor...