The aim of the study was to determine the effect of tetramethylpyrazine phosphate tablets (TPT), a Chinese medicine used for cardiovascular disease, on immunity activity and oxidative injury in rats. Heart failure (HF) was induced by isoproterenol (ISO). After the animal model was established, the rats were administered the TPT by gavage (once a day). The results indicated that TPT improved lef...

Smutna M., o. Synek: Lipid Peroxidation in Semen of the Boar. Acta vet. Bmo, 48, 1979: 35-43. During the catalyzed aerobic incubation of the complete boar semen malonyldialdehyde (MDA) is produced. MDA is a good indicator of peroxidative decomposition of polyunsaturated fatty acids. Detection of peroxidation products was conducted both by colour reaction with 2-thiobarbituric acid (evidence of ...

Chronic venous disease (CVD) encompasses a set of disorders the system that have high prevalence in Western societies and are associated with significant sociohealth costs. Pregnancy is period which different hormonal haemodynamic changes occur lead to cardiovascular system, increasing risk developing problems, especially during third trimester gestation. In turn, CVD involves series local syst...

In order to find a prophylactic supplementation for individuals who are at risk of exposure to ionizing radiation, we attempted to evaluate the effect of Vitamin E (Vit-E), a biological free radical scavenger, on restoration of hepatic lipid peroxidation (LPO) and lipid profile (LP) changes induced by sublethal g- radiation in BALB/c mice. The concentrations of cholesterol and phospholipid were...

The aim of the study is to validate a cell culture model appropriate for assessing the effects of standard nutritional formulas on neutrophil functionality in vitro. The model consists of aged cells exposed to a commercial nutritional formula containing solely LCT as lipid component. Preliminary experiments determined dosage of formula and culture interval. Neutrophils were isolated from a pool...

BACKGROUND Periodontal disease in cats is a local disease that may have systemic consequences that are affected by treatment. OBJECTIVE To test the hypotheses that systemic health indices would be correlated with the severity of periodontitis, and would improve with treatment. ANIMALS AND METHODS Apparently otherwise healthy cats from an in-bred colony were randomly assigned to a treatment ...

Reactive oxygen species (ROS) generated from UV-B radiation have the capacity to cause oxidative decomposition which leads to the formation of toxic components as well as lipid peroxidation. Considering this fact, the present study was performed to evaluate the effect of a cream (O/W) containing the essential oil of Calendula officinalis on biochemical parameters of the skin of albino rats agai...

OBJECTIVE To evaluate the effect of high dose phenobarbital on lipid peroxidation and antioxidant enzymes in perinatal asphyxia. DESIGN Open label, Randomized controlled trial. SETTING Neonatal intensive care unit of a tertiary care teaching hospital. PARTICIPANTS 72 full term inborn neonates with severe birth asphyxia. METHODS Neonates were randomized to Study (phenobarbital) group and...

We previously showed that the increase in nitric oxide (NO) levels and NO synthase (NOS) expression correlate with the progression of reactive astrocytosis and demyelination in the brains of 6-month-old taiep rats. Increased levels of NO can result in high concentration of peroxynitrite and thus cause tissue damage, which consists of lipoperoxidation of the cytoplasmic membrane, such as the mye...