Excess manganese (Mn) is neurotoxic. Increased manganese stores in the brain are associated with a number of behavioral problems, including motor dysfunction, memory loss and psychiatric disorders. We previously showed that the transport and neurotoxicity of manganese after intranasal instillation of the metal are altered in Hfe-deficient mice, a mouse model of the iron overload disorder heredi...

Calcium protection against lead and manganese toxicity Abstract Chronic exposure to lead (Pb) or manganese (Mn) is known to alter variety of neurological and behavioral functions. In this study, we have examined the neuro-behavioral perturbations in rats exposed to both Pb and Mn, and the protective effect of calcium supplement. Rats (3 months old) were exposed to Pb (0.2% through drinking wate...

we have prepared and characterized a few mn (iii) complexes by using a few bidentate and tridentate ligands. spectra of the manganese (abstract we have prepared and characterized a few mn (iii) complexes by using a few bidentate and tridentate ligands. spectra of the manganese (iii) ion in a variety of molecular environments are reported . on the basis of solution spectra, some of these complex...

A series of new manganese phosphonate clusters with unprecedented topologies, [Mn(20)Na(4)O(12)(t-BuPO(3))(12)(O(2)CMe)(16)(H(2)O)(12)].5H(2)O (), [Mn(15)O(6)(MePO(3))(2)(MeCOO)(18)(H(2)O)(12)][MePO(3)H](2).12H(2)O (), and [Mn(t-BuPO(3)H)(2)(phen)(2)].MeCOOH () have been synthesized and characterized. The core of is composed of two folded "butterfly-like" [Mn(4)(mu(3)-O)(2)] units and two trigo...

Density functional theory calculations were performed to study the structure and magnetic properties of bcc (α) and fcc (γ) Fe with 3 at.% carbon and manganese impurities. We find that all bcc-based Fe, Fe-C and Fe-Mn-C phases exhibit a ferromagnetic (FM) ground state, while the antiferromagnetic double-layer (AFMD) state is lowest in energy within the collinear spin approach in fcc Fe, Fe-C an...

the characteristics of manganese and iron binding to human apotransferrin (apo-tf) have been investigated and compared in this study. both metal ions were taken up by human apo-tf and formed complexes, with the maximum absorbances observed at 410 and 340 nm for manganese-transferrin (mn-tf) and 465 nm for iron-transferrin (fe-tf). addition of manganese (1.5 µg/ml) to the reaction mixture contai...

Rock varnish is generally understood to be a 5-500 micrometer thick nanostratigraphic coating consisting of approximately 70% clay glued together by 30% iron and manganese oxides, which forms on the surfaces of rocks in most semi-arid to hyper-arid climates. Many investigators believe that manganese exists in rock varnish mainly as birnessite, and that varnish has at least a partial biological ...

Manganese is capable of forming complex ions with many substances found naturally in the body (1). It seems reasonable to assume, therefore, that manganese injected as MnSO4 (hereafter referred to as "ionic manganese") will be complexed in the body to a varying extent shortly after administration. If the Mn is strongly chelated before it is injected, a state of competition between ligands is se...

Manganese is capable of forming complex ions with many substances found naturally in the body (1). It seems reasonable to assume, therefore, that manganese injected as MnSO4 (hereafter referred to as "ionic manganese") will be complexed in the body to a varying extent shortly after administration. If the Mn is strongly chelated before it is injected, a state of competition between ligands is se...

First-principles calculations were performed to study the structural, electronic, and magnetic properties of bcc Fe with C impurities alloyed with 2, 3, and 6 at.% of Mn. Our results reveal that both manganese concentration and carbon location with respect to Mn affect the Fe-Mn magnetic interaction. With an increase in Mn concentration in bcc Fe-Mn alloy, the local magnetic moment of manganese...