The acaricidal efficacy of afoxolaner (NexGard(®), Merial) was evaluated against Sarcoptes scabiei var. canis in a field efficacy study, when administered orally at a minimum dose of 2.5 mg/kg to dogs naturally infested with the mites. Twenty mixed-breed dogs of either sex (6 males and 14 females), aged over 6 months and weighing 4-18 kg, were studied in this randomised controlled field efficac...

The mite Sarcoptes scabiei causes sarcoptic mange (or scabies), a disease of considerable human and veterinary significance. An S. scabiei cDNA clone of about 2 kb was isolated from a S. scabiei var. hominis expression library by immunological screening using blood serum from a naturally infected chamois (Rupicapra rupicapra). The nucleotide sequence of the identified cDNA contains an open read...

Mange caused by Sarcoptes scabiei var. vulpes appeared among red foxes (Vulpes vulpes) in Scandinavia (south-west Finland) for the first time in this century in 1967. The disease was most probably introduced by foxes crossing the Gulf of Finland from Estonia. The mange epizootic spread northwards through Finland and reached Sweden in late 1975, when mangy foxes appeared in the northern part of ...

Rapid declines in red fox Vulpes vulpes populations have followed outbreaks of epizootic mange caused by the mite Sarcoptes scabiei. In Sweden, first outbreak sarcoptic started 1977/1978 and affected whole country 1984. Here we used data on number harvested foxes (51 480) from Gävleborg county (18 199 km2) Sweden between 1970 1994. We prevalence a sample (2694) 1974 to 1982. A rapid decline occ...

Notoedric mange was responsible for a population decline of bobcats ( Lynx rufus ) in 2 Southern California counties from 2002-2006 and is now reported to affect bobcats in Northern and Southern California. With this study we document clinical laboratory and necropsy findings for bobcats with mange. Bobcats in this study included free-ranging bobcats with mange (n = 34), a control group of free...

Sarcoptic mange in sheep, causes heavy losses in quantity and quality of wool and meat production.The present investigation aimed at evaluating the oxidative stress-antioxidant defense and erythrocytic membrane responses during sarcoptic mange in sheep.A bio-organic therapy (BT) was evaluated for its efficacy. Tocopherol was assessed for its antioxidant adjunctive potential. Materials and Metho...

Concern about emerging diseases has risen in recent years, and multihost situations have become increasingly relevant for wildlife management and conservation. We present data on Asturias, northern Spain, where 80 mangy red deer (Cervus elaphus) have been found since the beginning of the epizootic in chamois (Rupicapra pyrenaica parva) in 1993. We combine field and necropsy data with the result...

We documented sarcoptic mange caused by mites (Sarcoptes scabiei) in 22 gray wolves (Canis lupus) in the northern Rocky Mountain states of Montana (n=16) and Wyoming (n=6), from 2002 through 2008. To our knowledge, this is the first report of sarcoptic mange in wolves in Montana or Wyoming in recent times. In addition to confirming sarcoptic mange, we recorded field observations of 40 wolves in...