Bipolar affective disorder is a serious mental disease associated with significant morbidity and mortality. Good-quality research available to guide treatment strategies remains insufficient, particularly with regard to manic or hypomanic episodes. A critical review of the various stages of mania might be helpful for pharmaceutical companies and investigators as a prerequisite for the clinical ...

OBJECTIVE In this study patients were examined during the first year after traumatic brain injury to determine the presence of secondary mania. METHOD A consecutive series of 66 patients with closed-head injury were evaluated in the hospital and at 3-, 6-, and 12-month follow-ups. The patients were examined with a semistructured psychiatric interview and scales for measurement of impairment i...

OBJECTIVES To investigate the association between antidepressant therapy and the later onset of mania/bipolar disorder. DESIGN Retrospective cohort study using an anonymised electronic health record case register. SETTING South London and Maudsley National Health Service (NHS) Trust (SLaM), a large provider of inpatient and community mental healthcare in the UK. PARTICIPANTS 21,012 adults...

INTRODUCTION An investigation of the proportion of patients who have experienced mania with antidepressant treatment and their characteristics would seem to be of clinical use. AIMS The purpose of this clinical study was to examine the predictors of induction of mania in depression patients as a result of paroxetine treatment. METHOD A retrospective cohort analysis was carried out among dep...

A 12 year old boy presented with the clinical picture of secondary mania. Neuropsychological examination revealed significant prefrontal disturbance. The overlap in the clinical presentation of secondary mania and frontal lobe syndromes is highlighted. At least some of the so called frontal lobe syndromes can he considered as secondary mania.

Mood disorders (unipolar and bipolar disorders) are one of the most distressing and disabling disorders known to man kind. Mood disorders may present as either a depressive phase or manic phase. Chronic mania by definition means presence of manic symptoms in excess of 2 yrs without remission. Chronic mania differs in its psychopathological presentation from the acute mania. Chronic mania also p...

BACKGROUND The major diagnostic classifications consider mania as a uni-dimensional illness. Factor analytic studies of acute mania are fewer compared to schizophrenia and depression. Evidence from factor analysis suggests more categories or subtypes than what is included in the classification systems. Studies have found that these factors can predict differences in treatment response and progn...

Mania following or associated with medical and pharmacological conditions is well known. However there are not too many reports of mania following typhoid fever. This paper describes a mania syndrome following successfully treated typhoid fever in a young male without any past or family history of psychiatric illness or associated psychosocial stressors.