BACKGROUND It is not known whether premenopausal women who report low sexual satisfaction and have low circulating testosterone levels will benefit from testosterone therapy. OBJECTIVE To evaluate the effects of exogenous testosterone in premenopausal women reporting diminished sexual function. DESIGN Randomized, double-blind, placebo-controlled, dose-ranging trial. SETTING 6 Australian m...

Many recent disease outbreaks (e.g. SARS, foot-and-mouth disease) exhibit superspreading, where relatively few individuals cause a large number of secondary cases. Epidemic models have previously treated this as a demographic phenomenon where each individual has an infectivity allocated at random from some distribution. Here, it is shown that superspreading can also be regarded as being caused ...

OBJECTIVE To synthesize the literature on youth suicide risk factors (RFs) and prevention strategies (PSs); evaluate quality of information regarding youth suicide RFs and PSs found on selected Canadian websites; determine if website source was related to evidence-based rating (EBR); and determine the association of website quality indicators with EBR. METHODS Five systematic reviews of youth...

Abstract Along the Nankai Trough subduction zone, southwest Japan, short-term slow slip events (SSEs) are commonly detected in strain and tilt records. These observational data have been used rectangular fault models with uniform to analyze SSEs; however, assumption of precludes possibility mapping distribution detail. We report here an inversion method, based on joint use evaluated terms Akaik...

Various types of slow earthquakes occur in the Nankai subduction zone, among which slip events (SSEs) seem to connect shallow and deep part plate further trigger seismic or aseismic transients surrounding areas. This study uses a version space-time epidemic-type aftershock sequence (ETAS) model with non-stationary background rate detect earthquake swarms that may be related SSEs region. We 999 ...

INTRODUCTION Recently, there has been much discussion in the literature about how to determine the meaningfulness of results generated from a patient-reported outcome measure. A number of reviews have shown that there are two main approaches: anchor- and distribution-based approaches for determining the minimum important difference (MID) for a new measure. There are issues with calculating an M...

OBJECTIVES Occupational health service (OHS) for small-scale enterprises (SSEs) is still limited in many countries. Both Japan and the Netherlands have universal OHS systems for all employees. The objective of this survey was to examine the activities of occupational physicians (OPs) in the two countries for SSEs and to investigate their proposals for the improvement of service. METHODS Quest...

Assessing structural similarity and defining common regions through comparison of protein spatial structures is an important task in functional and evolutionary studies of proteins. There are many servers that compare structures and define sub-structures in common between proteins through superposition and closeness of either coordinates or contacts. However, a natural way to analyze a structur...

Abstract Rechargeable all-solid-state batteries (ASSBs) are considered to be the next generation of devices for electrochemical energy storage. The development solid-state electrolytes (SSEs) is one most crucial subjects in field storage chemistry. newly emerging halide SSEs have recently been intensively studied application ASSBs due their favorable combination high ionic conductivity, excepti...

Solid-state Li–air batteries with ultrahigh energy density and safety are promising for long-range electric vehicles special electronics. However, the challenging issues of developing battery-oriented solid-state electrolytes (SSEs) high ionic conductivity, interfacial compatibility, stability to boost reversibility, increase stable triple-phase boundaries, protect Li anode in an open system su...