aneurysmal bone cyst (abc) is a benign expansile bone tumor, most commonly involving the medulla of long bones. abc rarely arises within the cortex or in the subperiosteal region, radiographically mimicking other conditions, in particular surface osteosarcomathat is low-grade in nature and may go secondary abc changes, and telangiectatic osteosarcoma. both of these are sometimes mistaken micros...

Bisphosphonates are the most prescribed preventative treatment for osteoporosis. However, their long-term use has recently been associated with atypical fractures of cortical bone in patients who present with low-energy induced breaks of unclear pathophysiology. The effects of bisphosphonates on the mechanical properties of cortical bone have been exclusively studied under simple, monotonic, qu...

INTRODUCTION A variation in bone response to fluoride (F(-)) exposure has been attributed to genetic factors. Increasing fluoride doses (0 ppm, 25 ppm, 50 ppm, 100 ppm) for three inbred mouse strains with different susceptibilities to developing dental enamel fluorosis (A/J, a "susceptible" strain; SWR/J, an "intermediate" strain; 129P3/J, a "resistant" strain) had different effects on their co...

The variability assessment of the rib bone mechanical properties during the growth process is still missing. These properties could not be obtained in vivo on children. Relationships have been obtained between Hounsfield Units from computed tomography (CT) and mechanical properties (e.g. for the cortical bone on adults). As a first step for investigation of the mechanical propertie...

Magnesium and magnesium alloys have great application potential in the field of orthopaedics. Compared with traditional inorganic nonmetallic materials medical polymer materials, many advantages, such as better strength, toughness, fatigue resistance, easy processing. Its mechanical properties are suitable controllable. It can meet same elastic modulus, cell compatibility, biodegradability huma...

There are generally two types of bone tissue: trabecular and cortical. Cortical bone is the more dense tissue found on the surface of bones and trabecular bone is a highly porous structure that fills the proximal and distal ends of all long bones (e.g. femur or tibia) and is also present as a filler in other bones (e.g. in vertebral bodies). While at themolecular level both the cortical and tra...

Overweight and obesity are rapidly expanding health problems in children and adolescents. Obesity is associated with greater bone mineral content that might be expected to protect against fracture, which has been observed in adults. Paradoxically, however, the incidence of bone fractures has been found to increase in overweight and obese children and adolescents. Prior studies have shown some r...

INTRODUCTION Predominant collagen fiber orientation (CFO) can significantly influence the mechanical properties of cortical bone (e.g., Martin and Ishida, 1989; Martin and Broadman, 1993; Riggs et al., 1993). Previous studies have demonstrated that CFO is a strong predictor of tensile, compressive, or bending strength. Few of these studies, however, have examined the relative effects of CFO, m...

Accurate measurements of physical characteristics of bone are essential for diagnosis, assessment of change following treatment, and therefore, indirectly, for evaluation of new forms of therapy. This is particularly true of osteoporosis and aging skeleton, in which fractures occur easily. Methods: In this study an ultrasonic system was set-up and calibrated on Plexiglas tubes of variable thick...

Anisotropy is one of the most peculiar aspects of cortical bone mechanics; however, its anisotropic mechanical behaviour should be treated only with strict relationship to the length scale of investigation. In this study, we focus on quantifying the orientation and size dependence of the spatial mechanical modulation in individual secondary osteons of bovine cortical bone using nanoindentation....