The vast majority of teratomas originating from more than a single germ layer are benign. Often, such teratomas are initially asymptomatic. Later symptoms are caused by the weight per se of the teratoma and include chest pain, cough, dyspnea, and/or recurrent attacks of pneumonia. A mediastinal teratoma is treated by total surgical resection of the mass. Here, we report a case of giant mature c...

Primary pulmonary teratoma is a very rare disease. Most follow a benign course and are incidental findings during routine chest X-rays. Hair found in sputum or in bronchus detected during bronchoscopy is also a rare condition and is usually caused by mediastinal teratoma. This case report is of a 36-year-old man who presented with halitosis. A fiber-optic bronchoscopy revealed coarse hair origi...

A teratoma, by definition, is a true tumour or neoplasm composed of multiple tissues of kinds foreign to the part in which it arises. In a series of 82 cases Willis (1953) quotes the following sites of origin: ovary, 50, and testes 19, the remainder being epididymal, retroperitoneal, pre-sacral, anterior mediastinal, intrapericardial and cerebral. A careful search of the literature failed to re...

We report a challenging case of a newborn with a massive anterior mediastinal teratoma (MT), occupying nearly the right hemithorax, presenting at birth with life threatening respiratory distress (RD). Optimal approach and outcome was achieved with a coordinated, multidisciplinary approach.

Here, we report the case of a patient with a slowly-progressing anterior mediastinal teratoma submitted to surgical resection. The anatomopathological examination of the sample revealed malignant degeneration to carcinoid tumor. Such evolution is very rare, and we have found only three related studies in the literature. We describe the clinicopathological features of the tumor and discuss the t...

Background Anti-N-methyl- d-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune neurological disorder that usually occurs as a paraneoplastic syndrome and is particularly associated with ovarian teratoma. Standard therapy for severe cases is not established and the prognosis in patients who do not respond to first-line treatment is poor. Case Report An 11-year-old boy complained ps...

A mediastinal germ cell tumor with a sarcomatous component is extremely rare and is accompanied by a poor prognosis. Clinical and radiologic diagnosis is very difficult. Herein, we report a rare case of anterior mediastinal malignant teratoma containing a growing liposarcomatous component and detail the diagnostic process. The case was diagnosed by repeated transthoracic needle biopsy and corre...

Teratomas are germ cell tumors, manifested with a great variety of clinical features; the most common extragonadal site is the anterior mediastinum. In this case, we report the patient with a large mature mediastinal teratoma with several components of ectodermal and endothermal epithelium. A 24-year-old female patient presented with history of persistent chest pain and progressively aggravatin...