6 ORIGINAL PAPERS 7 ABBREVIATIONS 8 INTRODUCTION 9 Presentation 9 History 11 Cochlear anatomy 12 Cochlear physiology 14 Cochlear innervation 16 The sensory auditory systems 19 The spiral ganglion 21 Specific characteristics of the human spiral ganglion 23 Tight and gap junctions 27 OBJECTIVES OF THE STUDIES 29 MATERIAL AND METHODS 30 RESULTS 36 Preservation 36 Light microscopic studies and TEM ...

The medial preoptic nucleus (MPN) of the hypothalamus plays a major role in many functions involved in maintaining bodily homeostasis, such as thermoregulation and osmoregulation, as well as in the control of complex behaviours, e.g. sexual behaviour. A fundamental basis for the control and execution of these functions is the synaptic communication between neurons of the MPN. However, the funct...

Cystinuria is defined as an inherited disorder characterised by increased urinary excretion of cystine and the dibasic amino acids arginine, lysine and ornithine. The only clinical manifestation of cystinuria is renal cystine stone formation due to the low solubility of cystine in the urine. Cystinuria can be attributed to mutations in the SLC3A1 and SLC7A9 genes in the majority of all cases an...

Malignant melanoma arises from the pigment producing melanocytes in epidermis and is the most aggressive type of skin cancer. The incidence of malignant melanoma is increasing faster than any other type of cancer in white population worldwide, with a doubling rate every 10-20 years. So far, the only identified external risk factor for malignant melanoma is UV exposure. Elimination of photodamag...

.............................................................................................................................. 7 INTRODUCTION...................................................................................................................... 8 Streptococcus agalactiae ............................................................................................ 8 S. agalactiae d...

5 List of Original papers 7 Abbreviations 8 Introduction 9 Volleyball 9 History 9 Game characteristics 9 Physical demands 11 General injury pattern in volleyball 12 Olympic weightlifting 14 History 14 Characteristics 14 Physical demands 14 General injury pattern 15 The normal patellar tendon 16 Anatomy 16 Blood supply 18 Metabolism 18 Innervation 19 Biomechanics 20 The chronic painful patellar ...

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................................................................................................. 6 ORIGINAL PAPERS .................................................................................... 8 INTRODUCTION ......................................................................................... 9 Work-related exposure.......................................................................

.............................................................................................................9 INTRODUCTION ..................................................................................................10 1 Regulation of transcription in eukaryotes ......................................................10 1.1 Recruitment of co-activators and co-repressors .......................