1. Ivermectin belongs to the macrocyclic lactone class of endectocides and consists of a mixture of two homologous compounds, 22,23-dihydroavermectin B1a (H2B1a, not less than 80%) and 22,23-dihydroavermectin B1b (H2B1b, not more than 20%). Avermectins are potent anthelmintic, insecticidal and acaracidal compounds which, by increasing the membrane permeability to chloride ions, mediate the para...

1. Avilamycin is an orthosomycin antibiotic complex produced by the fermentation of Streptomyces viridochromogenes. Orthosomycin antibiotics are divided into two groups: those that contain an aminocyclitol residue and those that are esters of dichlorisoeverninic acid. Avilamycin falls into the latter group as do the evernimicins. Avilamycin is primarily active against gram-positive bacteria. Th...

BACKGROUND Acceptance of generic medicines by patients is an essential factor given that they are the end users of these medicines. In fact, adequate knowledge and positive perceptions are prerequisite to patients' acceptance and use of generic medicines. OBJECTIVE To assess the current belief and views of patients about generic medicines in Malaysia. METHOD This was a self-administered que...

1 who work for the industry-funded Hudson Institute, advocate the use of patented drugs, pointing to what they say are risks associated with generic drugs. They confuse generic drugs with old, substandard, ineffective, and counterfeit drugs. Generic does not mean old. The 1996 World Trade Organisation (WTO) Agreements mandate all member countries to provide 20-year patent protection for medicin...

Residents in care homes are more likely to be prescribed multiple medicines yet often have little involvement in these prescribing decisions. Reviewing and stopping inappropriate medicines is not currently adopted across the health economy. This Health Foundation funded Shine project developed a pragmatic approach to optimising medicines in care homes while involving all residents in decision m...

background the unregulated availability and irrational use of tuberculosis (tb) medicines is a major issue of public health concern globally. governments of many low- and middle-income countries (lmics) have committed to regulating the quality and availability of tb medicines, but with variable success. regulation of tb medicines remains an intractable challenge in many settings, but the reason...

Introduction Generic medicines are an important policy option to reduce out-of-pocket expenditure on medicines. However, negative perceptions of their quality affect utilisation and raise issues of confidence and trust in medicines and health services. The aim of the study was to test the quality of generic and branded medicines and explain negative perceptions towards generic medicines. Meth...

OBJECTIVE To assess the magnitude of price difference between generic and innovator medicines and to evaluate the effect of the price competition between them. METHODS From January 2000 to June 2004, 135 generic medicines and their respective innovator medicines were followed up for a period of up to four years. Prices were extracted from pharmaceutical market specific publications and record...

myxomas, the most common primary cardiac tumors, are known as a source of cardiogenic emboli. the possibility of their early detection has made them of great importance for emergency medicines. detection of the disease is probable at early stages using echocardiography and associate complications such as syncope, cerebral embolic ischemic strokes, and sudden death. we report experience of a rar...