Infectious diseases are common world wide, especially in developing countries. Some of these are relatively easy to diagnose at the bedside on the clinical picture alone (e.g. Measles, mumps, chicken pox). Some infections produce localising signs (e.g. Neck stiffness in meningitis, pain and tenderness over mastoids, sinuses, bone and joints, pleurisy, pneumonia, gall bladder and appendix), whic...

A case of typhus fever is presented. On admission, the clinical diagnosis was typhoid fever. Forty-eight hours after admission, the presence of subconjunctival haemorrhage, malena, and jaundice raised the possibility of a different aetiology, the two most likely differentials being dengue and typhus. Finally, a co-infection of typhoid and typhus was discovered. This uncommon clinical scenario s...

Background. Malaria and typhoid fever are major public health problems in tropical and subtropical countries. People in endemic areas are at risk of contracting both infections concurrently. Objectives. The study was aimed at determining the prevalence and associated risk factors of malaria, typhoid, and their coinfection among febrile patients. Methods. A cross-sectional study was conducted on...

BACKGROUND Typhoid and paratyphoid fever remain important causes of morbidity worldwide. Accurate disease burden estimates are needed to guide policy decisions and prevention and control strategies. METHODS We conducted a systematic literature review of the PubMed and Scopus databases using pre-defined criteria to identify population-based studies with typhoid fever incidence data published b...

We evaluated the reliability of a passive bacterial agglutination test to detect Salmonella typhi somatic antigen(s) in the sera of patients with typhoid fever. It was positive in 32 of 33 bacteriologically proven typhoid fever cases. Among 13 patients with a presumptive diagnosis of typhoid fever, 11 were positive by passive bacterial agglutination. The serum of one patient with paratyphoid A ...

Hemophagocytic syndrome is a non-malignant process that is characterized clinically by fever, hepatomegaly, splenomegaly, pancytopenia in peripheral blood, and reactive histiocytes in the bone marrow. Bacterial infectious diseases like typhoid fever and brucellosis and viral infections including CMV, herpes viruses, and Epstein-Barr virus are diagnosed as the cause of this syndrome. In thi...

BACKGROUND The bacterium Salmonella enterica serovar Typhi causes typhoid fever, which is typically associated with fever and abdominal pain. An outbreak of typhoid fever in Malawi-Mozambique in 2009 was notable for a high proportion of neurologic illness. OBJECTIVE Describe neurologic features complicating typhoid fever during an outbreak in Malawi-Mozambique METHODS Persons meeting a clin...

Typhoid fever is a systemic life-threatening infection caused by the bacterium Salmonella enterica serotype Typhi occurring more frequently in underdeveloped regions of the world due to overcrowding and poor sanitation. Initiation of appropriate therapy decreases severity and clinical outcome of the disease which requires early and accurate diagnosis. Pathogenesis due to typhoid leads to variou...

IN the year ending on the 31st December, 1952, there were one hundred and twelve cases of acute poliomyelitis admitted to the Northern Ireland Fever Hospital. One hundred and eleven patients were admitted as suspected cases of poliomyelitis. Of these the diagnosis was correct in seventy-one. In the forty in whom the diagnosis was not confirmed no distinctive condition could be found in twenty-t...