Pharmacognosy Research,2022,14,1,1-4.DOI:10.5530/pres.14.1.1Published:December 2021Type:Original ArticleAuthors:Sabri Benkermiche, Samir Djemli, Meriem Haloui, Mohamed Lamine Benabed, and Abdelkrim Tahraoui Author(s) affiliations:Sabri Benkermiche1, Djemli1,*, Haloui2, Benabed1, Tahraoui1 1Applied Neuroendocrinology Laboratory, Department of Biology, Faculty Sciences, Badji Mokhtar Annaba Unive...

A 7.9-kilobase (kb) chromosomal fragment was cloned from a mercury-resistant Bacillus sp. In Escherichia coli, in the presence of a second plasmid carrying functional transport genes, resistance to HgCl2 and to phenylmercury acetate (PMA) was expressed. Shortening the cloned fragment to 3.8 kb abolished resistance to PMA but not to HgCl2. In Bacillus subtilis, the 3.8-kb fragment produced mercu...

Mercuric chloride (HgCl2) is an environmental and industrial toxicant that affects many tissues. Considering oxidative stress is an important component of mercury induced hepatotoxicity, antioxidants are expected to play a protective role against it. The present study was designed to investigate the probable effects of pomegranate seed oil (PSO) on hepatotoxicity induced by HgCl2 administration...

Monoclonal antibodies (mAbs) that react with soluble mercuric ions have been produced by injection of BALB/c mice with a hapten-carrier complex designed to maximize exposure of the metal to the immune system. Three hybridomas producing antibodies that reacted with bovine serum albumin (BSA)-glutathione-HgCl, but not with BSA-glutathione, were isolated from the spleen of a mouse given multiple i...

Aquaporins play a major role in governing the movement of water between neighboring cells during seed germination and are major players in response to abiotic stress conditions that affect water availability. Seeds of pea (Pisum sativum L. cv. Arkel) were used for studying cell growth, expression and function of aquaporins during seed imbibition, radicle emergence and growth.Water channel funct...

Inorganic mercury, though a key component of pediatric vaccines, is an environmental toxicant threatening human health via accumulating oxidative stress in part. Luteolin has been of great interest because of its antiinflammatory, anticarcinogenic and antioxidative effects. Here we hypothesized that luteolin would attenuate hepatotoxicity induced by acute inorganic mercury exposure. Kunming mic...

Increasing data suggest that mitochondrial dysfunction may be an important early component of nephrotoxin-induced changes in renal cell function and viability. This study was designed to obtain more detailed information about the effects on several basic bioenergetic parameters of the direct interaction of Hg2+ with renal cortical mitochondria in vitro as a necessary prelude to studies of mitoc...

Effect of Garlic against mercuric chloride induced toxicity in albino rats was studied. Oral administration of mercuric chloride (100mg/kg/p.o) for 30 days resulted in significant increase in LPO Basal level and LPO FeSO(4) induced and significant decrease in GSH (Glutathione) and Vit C as compared to the normal and control group. Simultaneous administration of Garlic along with Mercuric chlori...

Backgroud. Mercuric sulfide (HgS) has been used in traditional medicines for thousands of years, such as cinnabar, Zuotai and so on. Increasing research supports that HgS is different from mercury chloride (HgCl2) and methylmercury (MeHg) in toxicity and pharmacology, due to the differences in chemical forms. However, the differences of the cytotoxicity and endoplasmic reticulum stress (ERs) am...

Mercuric chloride (HgCl2) is a common heavy-metal pollutant widely used in commercial products and industry, but its excessive use uncontrolled discharge have caused great harm to aquatic environments human health. To research the mechanisms of HgCl2 toxicity organisms, this study cultured green alga Scenedesmus quadricauda gradient concentrations (0, 0.1, 0.3, 0.5, 0.7, 0.9 mg/L) for 9 days. T...