Three cases of ketoacidosis in previously unsuspected diabetics are described. Each was admitted to hospital as a neurosurgical emergency. The recognition of this rare presentation is stressed since prompt treatment of the metabolic disturbance rapidly resolves the neurological abnormality.

Altered metabolism is one of the hallmarks of cancer cells. The best-known metabolic abnormality in cancer cells is the Warburg effect, which demonstrates an increased glycolysis even in the presence of oxygen. However, tumor-related metabolic abnormalities are not limited to altered balance between glucose fermentation and oxidative phosphorylation. Key tumor genes such as p53 and c-myc are fo...

BACKGROUND The amount of body fat, rather than the amount of excess weight, determines the health risks of obesity, type 2 diabetes mellitus, and cardiovascular disease. AIMS To look at the association of body fat percentage with cardiometabolic risk factors in subjects with normal glucose tolerance (NGT). SETTINGS AND DESIGN Cross-section study from the Chennai Urban Rural Epidemiology Stu...

Alcaptonuria is a rare, hereditary, metabolic disorder characterized by a defect in the oxidation of tyrosine (l-3). In this condition homogentisic acid, an intermediary product of tyrosine degradation in mammalian liver, is excreted in the urine. This disorder has been attributed to an abnormality of the enzyme system, homogentisic acid oxidase, but the exact nature of the abnormality has not ...

Autism Spectrum Disorder (ASD), is a neurodevelopmental disorder which accompanied by several health-related challenges. Nutritional and gastrointestinal problems are common among individuals with ASD. Gut microbiota imbalance may be reason of nutritional including food selectivity restricted dietary intake. gut can increase behavioral symptoms the possibility necessity for medication. It has b...