A metabolic system consists of a number of reactions transforming molecules of one kind into another to provide the energy that living cells need. Based on the biochemical reaction principles, dynamic metabolic systems can be modeled by a group of coupled differential equations which consists of parameters, states (concentration of molecules involved), and reaction rates. Reaction rates are typ...

conclusions adherence to the meddiet, according to mds and sofi-mds, may not predict mets components and mets incidence after 3 years of follow-up in iranian adult populations. results after adjusting for potential confounders, neither higher mds nor higher sofi-mds were significantly associated with the mean values of mets components and the risk of metabolic abnormalities incidence after 3 ye...

Introduction: SIRT1 has attracted great interest due to its role as a regulator of longevity, and therapeutic potential for the prevention treatment aging age-related comorbidities. However, mechanisms by which influences course remain unknown. Methods: The study population included 88 apparently healthy subjects aged 31 – 65 without established atherosclerotic cardiovascular disease or metabol...