Hematopoietic pre-B-cell leukemia transcription factor-interacting protein (HPIP), is known to promote tumor development and metastasis. However its role in cervical cancer remains unknown. The purpose of this study was to investigate the clinical significance of HPIP expression and the prognosis of patients with cervical cancer. Fresh frozen tissues from 10 samples of cervical cancer and 8norm...

BACKGROUND Cervical cancer is the third most common cancer among women in Malaysia. The objective of this study was to estimate the effect of explanatory variables on survival time of cervical cancer patients receiving treatment at a hospital in Malaysia. METHODS In this retrospective record review study, cervical cancer data obtained from Hospital UniversitiSains Malaysia (HUSM) was analysed...

NEDD9, a focal adhesion scaffolding protein, has been recently proposed to regulate invasion and metastasis in some cancer types, but unknown in cervical cancer. The aim of this study was to determine if NEDD9 was involved in the progression and metastasis of cervical cancer. The experimental results showed NEDD9 protein was overexpressed in cervical cancer compared with normal cervical epithel...

malignant tumors of pancreas are usually primary neoplasms and pancreatic metastases are rare findings. we are reporting a case of squamous cell carcinoma (scc) of the esophagus with pancreatic metastasis. a 59-year old woman was admitted with chief complaint of abdominal pain and mass. she was a known case of esophageal scc since 4 years before when she had undergone transthoracic esophagectom...

meningioma is usually a benign central nervous system (cns) tumor. metastasis is rare; however if it does occur the most metastatic sites are the liver and lungs. here, two cases of cns meningioma with metastasis to cervical lymph nodes are reported. the first case, a 48 year-old man developed cervical lymph node metastasis nine years after primary tumor diagnosis. the second case, a 23 year-ol...

Programmed cell death 4 (PDCD4) is a tumor suppressor, and it inhibits tumor progression and metastasis. Even though down-regulation of PDCD4 has been implicated with many different types of human cancers, its roles in the progression of cervical cancer remain unexplored. Here, we have systematically examined the expression pattern of PDCD4 in cervical tissues. 15 cervical normal tissues, 14 ce...

The lung is a distant metastatic site of gynecologic cancers. These metastases have clinical characteristics which can be solitary, multiple, solid, or manifest by pleural effusion. Diagnosing and managing metastasis challenging because each type gynecological cancer has different characteristics. Some cancers tumor markers that help diagnose metastasis; however, others do not them. options for...