Different kinds of oxidants (free radicals) produced during aerobic metabolisms of fat, protein, carbohydrates and xenobiotics, not only create oxidative stress and damage to macromolecules but are implicated in the pathogenesis of several neurological, cardiovascular, musculoskeletal, carcinogenic and radiation related disorders, requiring their neutralization, amelioration or immunity boost u...

From time immemorial, for a large number of the world’s rural population, medicinal plants are the only source for the prevention and treatment of various pathological diseases. Medicinal plants and their constituents, vegetables, fruits and dietary fibre have been reported to prevent multistage carcinogenesis or may be destroying or blocking DNA damaging mutagens in the cells (Johnson, 1997; C...

The Fabaceae family (Leguminosae) consists of approximately 650 genera and 18,000 species, it is one of the largest Angiosperm families [1,2]. The genus Indigofera comprises around 700 species that are distributed geographically in tropical regions [3]. I. heterantha locally known as ghoreja or kainthaye (in Pashtho), Jangli methi (in Urdu) and Himalayan Indigo (in English) extensively spread i...

Diabetes mellitus is the most prevalent metabolic syndrome worldwide and is characterized by hyperglycemia resulting in various shortterm metabolic changes in lipid and protein metabolism and longterm irreversible vascular changes which include diabeticspecific complications viz., retinopathy, nephropathy and neuropathy. In the present study eleven patients of Type2 diabetes mellitus were surve...

The plant of Desmodium triflorum Linn (Fabaceae) are reported to have great medicinal value. The aim of this study to evaluate pharmacognostic evaluation including examination of morphological characters, ash value, powder analysis, and extractive values were carried out. Phytochemical screening including chemical examination and chromatographic study were also carried out. This would help to s...

The transcapillary net exchanges of inulin, para-ajiiinohippurate, thiocyanate and heavy water were determined in the renal circulation. It was found that the tracer substances larger than heavy water diffused more freely through renal than through previously studied peripheral or pulmonary capillaries. The results are consistent with the concept of a larger pore size in renal capillaries. P RE...

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Editorial The neonatal period is the time when a human being is most vulnerable to bacterial infections such as Staphylococcus au-reus, which is a major pathogen causing neonatal morbidity and mortality. Staphylococci, aerobic or facultative anaerobic gram-p...

V itamin B-12 is a cofactor for 2 enzymes. In the cytoplasm, methionine synthase requires vitamin B-12 in the form of methylcobalamin and catalyzes the conversion of homocysteine to methi-onine by transfer of a methyl group from methyltet-rahydrofolate. This enzyme links the methylation pathway through synthesis of the methyl donor S-adenosyl methionine and the pathway in which purine and pyrim...

Discussion This case history is of interest because of the diagnostic problems presented by the onset of haematuria during the course of severe staphy-lococcal septicaemia treated with massive doses of penicillin, since it may be a complication both of the disease and of the therapy. Haematuria may arise during the course of staphylococcal septicaemia but in this patient the onset was later tha...