The aims of your case report is to show the predictivity of (99m)Tc-sestamibi (MIBI) scintigraphy and doppler ultrasound imaging on secondary hyperparathyroidism (SHPT) in a patient responsive to calcimimetic treatment. Moreover, it has been reported that calcimimetic has great potential in reducing the volume of the parathyroid gland. On the other hand, the MIBI scintigraphy is considered a cr...

Parathyroid scintigraphy with 99mTc-sestamibi (MIBI) is an established technique for localising abnormal parathyroid glands (PGs). However, the identification and localisation of PGs require much attention from medical experts are time-consuming. Artificial intelligence methods can offer assisting solution. This retrospective study enrolled 632 patients who underwent double-phase thyroid subtra...

OBJECTIVE Primary hyperparathyroidism (pHPT) is characterised by increased parathyroid hormone (PTH) secretion and consequently increased plasma calcium. During the last few decades parathyroid scintigraphy (PS), is applied in almost all patients with pPHT before surgery and specifically before minimally invasive parathyroidectomy. The aim of this study was to find the best cut-off levels of to...

UNLABELLED 99mTc-pertechnetate scintigraphy plays an essential role in the management of a variety of thyroid and parathyroid disorders. The authors report an unusual case of mediastinal tracer distribution of 99mTc-pertechnetate and 99mTc-MIBI in relation to an oesophageal conduit following oesophago-gastrectomy and reconstructive surgery on thyroid scintigraphy. This is a rare but important c...

OBJECTIVE In this study, our aim was to study the efficiency of gamma probe guided minimally invasive parathyroidectomy (GP-MIP), conducted without the intra-operative quick parathyroid hormone (QPTH) measurement in the cases of solitary parathyroid adenomas (SPA) detected with USG and dual phase 99mTc-MIBI parathyroid scintigraphy (PS) in the preoperative period. MATERIAL AND METHODS This cl...

A 10-yr-old boy visited Minoh City Hospital complaining of gross hematuria. Laboratory investigations revealed hypercalcemia, hypophosphatemia, and elevated serum levels of parathyroid hormone. A stone was found in the right ureter with drip infusion pyelography. A parathyroid adenoma was successfully diagnosed with computed tomography, ultrasonography, and methoxy-2-isobutyl isonitrile (MIBI) ...

Multiple endocrine neoplasia type 1 (MEN1 or Wermer syndrome) is a rare hereditary disease, and especially its association with ectopic parathyroid adenomas even more. Defined As tumor developing in at least two glands including the anterior pituitary gland, duodeno-pancreatic tissue. This autosomal dominant pathology caused by mutation of NEM1 gene encoding suppressor menin located on chromoso...

UNLABELLED Our objective was to investigate the feasibility of subtraction for SPECT images of (99m)Tc-MIBI double-phase parathyroid scintigraphy. METHODS Fourteen patients with hyperparathyroidism were enrolled in the present study. Histopathologically, excised tissue specimens showed hyperplasia in 11 patients and adenoma in 3 patients. Both ultrasonography and (99m)Tc-sestamibi (MIBI) SPEC...

Primary hyperparathyroidism caused by parathyroid adenoma requires surgical resection. To confine the extent of surgery to very minimum and exclude an atypical location, preoperative imaging aims at identifying suspicious gland. For this purpose, Technetium-99m (99mTc)-sestamibi scintigraphy SPECT have become international standard, in inconclusive cases also with C-11 methionine F-18 choline P...