background one of the most important causes of mortality in developed and developing countries is coronary artery disease. coronary artery disease (cad) may develop by deposition of lipid, fibrous or calcified debris on the surface of the coronary artery lumen. fibrous plaque and calcified plaque may cause substantial stenosis of coronary arteries leading to ischemia of heart muscle while lipid...

OBJECTIVE Flexible and semi-flexible micro-endoscopes were used in cochlear scala tympani inspection , to explore their application in inner ear examination. METHOD Fifteen profound hearing loss patients preparing for cochlear implant were included in this study. During the operation, micro-endoscopy was performed after opening the cochlear scala tympani. And 1 mm diameter semi-flexible micro...

Microcalcification is one of the key symptoms facilitating early detection of breast cancer. In this paper image are acquisition from the mini mias database and perform various steps they are image enhancement, feature extraction and classification .In image enhancement the images are enhanced using filters and the features are extracted from the enhanced image using Gabor filter, and classify ...

Disruption of the major renal Na/phosphate (Pi) cotransporter gene, Npt2a, in mice leads to a substantial decrease in renal brush border membrane Na/Pi cotransport, hypophosphatemia and appropriate adaptive increases in renal 25-hydroxyvitamin D 3-1α-hydroxylase (1αOHase) activity and the serum concentration of 1,25-dihydroxyvitamin D 3 (1,25(OH) 2 D). The latter is associated with increased in...

BACKGROUND AND AIMS The arterial wall calcium score and circulating free DNA levels are now used in clinical practice as biomarkers of cardiovascular risk. Calcium phosphate apatite retention in the arterial wall necessitates precipitation on an anionic platform. Here, we explore the role of tissue-free DNA as such a platform. METHODS The first step consisted of histological observation of sa...

To gain a better understanding of the mechanisms that underpin aortic calcification, rodent models have been previously utilised. Regions of calcium and phosphate deposition are commonly visualised using labor-intensive two-dimensional histomorphometric techniques. In this study, we developed a novel micro-computed tomography (µCT) imaging protocol to quantify calcification in vascular tissues ...

AIMS Westernized countries face a growing burden of cardiovascular calcification and osteoporosis. Despite its vast clinical significance, the precise nature of this reciprocal relationship remains obscure. We hypothesize that cardiovascular calcification progresses with inflammation and inversely correlates with bone tissue mineral density (TMD). METHODS AND RESULTS Arterial, valvular, and b...

BACKGROUND Herniated discs may exhibit calcification, and calcified discs may complicate surgical treatment. However, the osteogenic potential and expression of osteogenic markers in degenerative discs of different degenerative grades are still unclear. Our purposes are to study the differences in calcification rate and osteogenic potential of herniated discs according to different degenerative...