Granulomatosis with Polyangitis (GPA), previously known as Wegener’s Granulomatosis, is a form of anti-neutrophil cytoplasmic antibodies (ANCA)-associated vascuilitis predominantly involving the upper and lower respiratory tract and kidneys. Tracheobronchial involvement in GPA can have varied manifestations which include airway inflammation, mucosal granulomas, tracheobronchial stenosis, trache...

Eosinophilic granulomatosis with polyangitis (EGPA; earlier called Churg-Strauss syndrome) is a small-vessel necrotising vasculitis typically characterised by asthma, lung infiltrates, extra-vascular necrotising granulomas and hyper-eosinophilia. Cardiac disease is a major contributor to disease-related deaths in EGPA. We describe the case of a 39-year-old woman with late onset asthma, allergic...

We presented a 38-year-old woman suffering from acute cerebral infarction due to arteritis limited to bilateral internal carotid arteries without a condition of giant cell arteritis or granulomatosis with polyangitis. Our case is unprecedented and characterized by a young woman with wall enhancement in the internal carotid arteries on contrast-enhanced magnetic resonance imaging (MRI), therapeu...

Case presentation We report the case of localised granulomatosis with polyangitis in a 27 year old Caucasian gentleman who presented with multiple cranial neuropathies. He reported diplopia, hearing loss, dysphagia and dysarthria due to involvement of VI, XIII, IX, X and XII cranial nerves. A cerebral MRI demonstrated pachymeningitis along with mastoid changes and additional diagnostic workup s...