نتایج جستجو برای: mineralocorticoid receptor
تعداد نتایج: 591331 فیلتر نتایج به سال:
We present the case of a 40-year-old woman who experienced severe hypertension during her first pregnancy. Hypertension persisted after delivery, prompting admission to Department Endocrinology and Metabolism at our hospital. Examination revealed an aldosterone-producing adenoma, she was diagnosed with primary aldosteronism. Her controlled using methyldopa. She became pregnant again in April 20...
Activation of the renin-angiotensin (Ang)-aldosterone system is involved in the pathology of vascular diseases. Although the blockade of the mineralocorticoid receptor protects against vascular diseases, its role in cerebral aneurysms remains to be elucidated. We treated female rats subjected to renal hypertension, increased hemodynamic stress, and estrogen deficiency for 3 months with the mine...
Hyperkalaemia continues to be a major hazard of mineralocorticoid receptor blockade in an effort to retard the progression of chronic kidney disease (CKD). In cardiac patients on mineralocorticoid receptor blockade, RLY-5016 which captures K(+) in the colon has been effective in reducing the risk of hyperkalaemia. This compound might be useful in CKD as well.
Striatin is a novel protein that interacts with steroid receptors and modifies rapid, nongenomic activity in vitro. We tested the hypothesis that striatin would in turn affect mineralocorticoid receptor function and consequently sodium, water, and blood pressure homeostasis in an animal model. We evaluated salt sensitivity of blood pressure in novel striatin heterozygote knockout mice. Compared...
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