CYP3A29 is the most important key enzyme for drug metabolism in pig's liver. Research of the characters of CYP3A29 mRNA expression in Chinese experimental miniature pig's livers is significant for evaluating it whether suitable for experimental model for drug metabolism mediated by human CYP3A4 enzyme. In this study, the levels of CYP3A29 mRNA expression in livers of Bama miniature pigs, Guizho...

BACKGROUND Hemodynamic assistance with a miniature intracardiac pump may fill the treatment gap between use of an intraaortic balloon pump (IABP) and the current, more invasive ventricular assist devices. The objective of this study was to compare the hemodynamic efficacy of a miniature intracardiac pump device with that of IABP. METHODS AND RESULTS Reversible acute mitral regurgitation (AMR)...

In this paper, we investigate relation between weak subdifferential and augmented normal cone. We define augmented normal cone via weak subdifferential and vice versa. The necessary conditions for the global maximum are also stated. We produce preliminary properties of augmented normal cones and discuss them via the distance function. Then we obtain the augmented normal cone for the indicator f...

‎The aim of this paper is to establish the equivalence between the concepts‎ ‎of an $S$-metric space and a cone $S$-metric space using some topological‎ ‎approaches‎. ‎We introduce a new notion of a $TVS$-cone $S$-metric space using‎ ‎some facts about topological vector spaces‎. ‎We see that the known results on‎ ‎cone $S$-metric spaces (or $N$-cone metric spaces) can be directly obtained‎ from...

Miniature neurotransmission is the transsynaptic process where single synaptic vesicles spontaneously released from presynaptic neurons induce miniature postsynaptic potentials. Since their discovery over 60 years ago, miniature events have been found at every chemical synapse studied. However, the in vivo necessity for these small-amplitude events has remained enigmatic. Here, we show that min...

Our theorems are on ordered cone metric spaces which are not necessarily normal. In the end, we describe the application of the main results in the integral equation.Although Du in [W‎. ‎S‎. ‎Du‎, ‎A note on cone metric fixed point theory and its equivalence‎, ‎Nonlinear Analysis‎, ‎72(2010) 2259-2261.]‎, ‎showed that the fixed point results in the setting of cone...