The ability to inhibit action is critical for everyday behavior and is affected by a variety of disorders. Behavioral control and response inhibition is thought to depend on a neural circuit that includes the dorsal striatum, yet the neural signals that lead to response inhibition and its failure are unclear. To address this issue, we recorded from neurons in rat dorsomedial striatum (mDS) in a...

Infidelity of translation of the genetic code has often been widely reported'-'2 in cell-free, protein-synthesizing systems derived from bacteria and, much less extensively,'3-'7 in cell-free systems. However, the degree by which experimental conditions per se contribute to the observed level of infidelity remains undetermined. Nevertheless, some studies on the influence of streptomycin on prot...

I evaluate the degree of misclassification error in Card and Hyslop’s (1997) method for identifying job stayers in the Current Population Survey (CPS). Benchmarking to job tenure data from the biennial CPS job tenure supplement, I find that Card and Hyslop’s method, which relies on industry and occupation codes, misclassifies approximately one-third of hourly workers. However, I also find that ...

The miscoding potential of N2,3-ethenoguanine (epsilon G), one of the carcinogen vinyl chloride adducts to DNA bases, has been examined by copying of poly (A, epsilon G) templates with DNA-dependent RNA polymerase and reverse transcriptase. In contrast to the results previously obtained with poly (C, epsilon G) templates where epsilon G acts as G and A, in poly (A, epsilon G) templates epsilon ...